- Oligonucleotides
- Nucleoside Analogs
- Uridine
Uridine
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Uridine (436)
- Formula: C9H11N5O4
- Molecular Weight: 253.21
6-Chloro-N1-(trimethylsilylethoxymethyl)pseudouridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents. 3’-Azido-3’-deoxy-4-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- Formula: C13H16F3N3O7
- Molecular Weight: 383.28
5-(N-Methyl-N-trifluoroacetyl)aminomethyl uridine is a nucleoside compound.
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- Formula: C8H9IN2O5
- Molecular Weight: 340.07
L-I-OddU, a L-5'-halo- dioxolane nucleoside analogue, is a potent and selective anti-Epstein-Barr virus (EBV) agent with an EC50 value of 0.03μM. L-I-OddU has low cytotoxicity with a CC50 value of 1000 nM. L-I-OddU has antiviral activity by suppressing replicative EBV DNA and viral protein synthesis.
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- Formula: C10H14N2O6
- Molecular Weight: 258.23
L-5-Methyluridine is the L-configuration of 5-Methyluridine (HY-W009444). 5-Methyluridine is an endogenous methylated nucleoside.
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- Formula: C9H11FN2O5
- Molecular Weight: 246.19
2'-Deoxy-2'-fluoro-l-uridine is an L-nucleoside compound. 2'-Deoxy-2'-fluoro-l-uridine is a potent, selective viral RNA polymerase inhibitor, thereby inhibiting RNA virus replication.
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- Formula: C15H26N2O5Si
- Molecular Weight: 342.46
5'-O-TBDMS-dU can be used in the synthesis of oligoribonucleotides.
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- Formula: C19H22N2O9
- Molecular Weight: 422.39
Kipukasin D is an natural nucleoside derived from Aspergillus versicolor with antibacterial activity.
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- Formula: C19H24N7O12P
- Molecular Weight: 573.41
Adenosyl-(3′→5′)-uridine (ApU) is a nucleotide, which is composed of an adenine base and a uracil sugar molecule through a 3'-5' phosphodiester bond. Adenosyl-(3′→5′)-uridine (ApU) participates in the biological processes, such as gene expression regulation, signal transduction, and protein synthesis.
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- Formula: C9H11IN2O5
- Molecular Weight: 354.10
2’-Deoxy-2’-iodouridine; 2’-Iodo-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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- Formula: C11H14N2O8
- Molecular Weight: 302.24
5-Carboxymethyluridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis.
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- Formula: C10H14N2O6
- Molecular Weight: 258.23
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- Formula: C21H42FN4O7P
- Molecular Weight: 512.55
2’-Deoxy-2’-fluorouridine 5’-monophosphate triethyl ammonium is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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- Formula: C23H19FN2O7
- Molecular Weight: 454.40
3’,5’-Bis-O-benzoyl-2’-deoxy-2’-fluoro-β-D-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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- Formula: C12H17N5O6
- Molecular Weight: 327.29
5-(3-Azidopropyl)uridine is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis. 5-(3-Azidopropyl)uridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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