OXi8007
Based on 1 Customer Validation
OXi8007 is a water-soluble phosphate proagent of OXi8006, a tubulin-binding compound.
For research use only. We do not sell to patients.
- Purity: 99.48%
- CAS No.: 288847-41-6
- Formula: C26H24NNa2O10P
- Molecular Weight:587.42
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| DU-145 | GI50 |
0.0297 μM
Compound: 33, OXi8007
|
Cytotoxicity against human DU145 cells by SRB assay
Cytotoxicity against human DU145 cells by SRB assay
|
[PMID: 24016002] |
| NCI-H460 | GI50 |
0.0311 μM
Compound: 33, OXi8007
|
Cytotoxicity against human NCI-H460 cells by SRB assay
Cytotoxicity against human NCI-H460 cells by SRB assay
|
[PMID: 24016002] |
| SK-OV-3 | GI50 |
0.0223 μM
Compound: 33, OXi8007
|
Cytotoxicity against human SKOV3 cells by SRB assay
Cytotoxicity against human SKOV3 cells by SRB assay
|
[PMID: 24016002] |
Chemical Information
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CAS No. 288847-41-6
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Appearance Solid
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Molecular Weight 587.42
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Formula C26H24NNa2O10P
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Color Off-white to light yellow
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SMILES
O=P(OC1=CC(C(NC2=C3C=CC(OC)=C2)=C3C(C4=CC(OC)=C(C(OC)=C4)OC)=O)=CC=C1OC)(O[Na])O[Na]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
H2O : ≥ 100 mg/mL (170.24 mM)
DMSO : 90 mg/mL (153.21 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 1.7024 mL | 8.5118 mL | 17.0236 mL | 42.5590 mL |
| 5 mM | 0.3405 mL | 1.7024 mL | 3.4047 mL | 8.5118 mL | |
| 10 mM | 0.1702 mL | 0.8512 mL | 1.7024 mL | 4.2559 mL | |
| 15 mM | 0.1135 mL | 0.5675 mL | 1.1349 mL | 2.8373 mL | |
| 20 mM | 0.0851 mL | 0.4256 mL | 0.8512 mL | 2.1279 mL | |
| 25 mM | 0.0681 mL | 0.3405 mL | 0.6809 mL | 1.7024 mL | |
| 30 mM | 0.0567 mL | 0.2837 mL | 0.5675 mL | 1.4186 mL | |
| 40 mM | 0.0426 mL | 0.2128 mL | 0.4256 mL | 1.0640 mL | |
| 50 mM | 0.0340 mL | 0.1702 mL | 0.3405 mL | 0.8512 mL | |
| 60 mM | 0.0284 mL | 0.1419 mL | 0.2837 mL | 0.7093 mL | |
| 80 mM | 0.0213 mL | 0.1064 mL | 0.2128 mL | 0.5320 mL | |
| 100 mM | 0.0170 mL | 0.0851 mL | 0.1702 mL | 0.4256 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.