2. Apoptosis NF-κB Metabolic Enzyme/Protease Immunology/Inflammation
  3. Apoptosis Reactive Oxygen Species
  4. Penduletin

Penduletin is a flavone, that can be isolated from Brickelia pendula and Vitex negundo. Penduletin shows anticancer activity. Penduletin induces apoptosis in the cancer cells through ROS generation.

For research use only. We do not sell to patients.

Penduletin Chemical Structure

Penduletin Chemical Structure

CAS No. : 569-80-2

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Based on 1 publication(s) in Google Scholar

Penduletin Related Antibodies

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Description

Penduletin is a flavone, that can be isolated from Brickelia pendula and Vitex negundo. Penduletin shows anticancer activity. Penduletin induces apoptosis in the cancer cells through ROS generation[1][2].

In Vitro

Penduletin (0-100 µg/mL, 48 h) shows antiproliferative activity against HepG2 and MCF-7 cell lines, with IC50 values of 25.8, and 6.4 µM, respectively[1].
Penduletin exhibits an enhanced ability to induce the cleavage of procaspase‐3 in HepG2 and both procaspase‐3 and procaspase‐8 in MCF-7 cells line[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Penduletin Related Antibodies
Molecular Weight

344.32

Formula

C18H16O7
CAS No.
SMILES

O=C1C2=C(O)C(OC)=C(OC)C=C2OC(C3=CC=C(O)C=C3)=C1OC
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Penduletin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Penduletin569-80-2ApoptosisReactive Oxygen SpeciesAnticancerHepG2MCF-7Inhibitorinhibitorinhibit

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