PF-4800567 hydrochloride

Cat. No.: HY-12470A: Data Sheet Handling Instructions
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PF-4800567 hydrochloride is a potent and selective inhibitor of?casein kinase?1? (CK1?), with an?IC₅₀?of 32 nM, which is greater than 20-fold selectivity over CK1δ (IC50, 711 nM). PF-4800567 hydrochloride is useful in probing unique roles between these two kinases in multiple signaling pathways.

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PF-4800567 hydrochloride 화학구조

CAS No. : 1391052-28-0

사이즈		재고
MOQ		Minimum order quantity
50 mg		견적 받기
100 mg		견적 받기
250 mg		견적 받기
Other size		견적 받기

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This product is a controlled substance and not for sale in your territory.

Other In-stock Forms of PF-4800567 hydrochloride:

PF-4800567

Other Forms of PF-4800567 hydrochloride:

PF-4800567 In-stock

2 Publications Citing Use of MCE PF-4800567 hydrochloride

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CK1 CK2

Biological Activity
순도&문서
References
고객리뷰

제품 설명	PF-4800567 hydrochloride is a potent and selective inhibitor of?casein kinase?1? (CK1?), with an?IC₅₀?of 32 nM, which is greater than 20-fold selectivity over CK1δ (IC50, 711 nM). PF-4800567 hydrochloride is useful in probing unique roles between these two kinases in multiple signaling pathways^[1].
IC₅₀ & Target	IC50: 32 nM ((CK1?)^[1]
분자량	396.27
화학식	C₁₇H₁₉Cl₂N₅O₂
CAS No.	1391052-28-0
SMILES	NC1=C2C(N(C3CCOCC3)N=C2COC4=CC=CC(Cl)=C4)=NC=N1.[H]Cl
선적	Room temperature in continental US; may vary elsewhere.
보관	Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서	Data Sheet (273 KB) Handling Instructions (2659 KB)
References	[1]. Walton KM, et al. Selective inhibition of casein kinase 1 epsilon minimally alters circadian clock period. J Pharmacol Exp Ther. 2009 Aug;330(2):430-9. [Content Brief]