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PF-5212374

(Synonyms: TRU-015)
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PF-5212374 (TRU-015) is a humanized antibody expressed in CHO, targeting CD20/MS4A1. PF-5212374 exhibits potent direct signaling and antibody-dependent cellular cytotoxicity, with complement-mediated cytotoxicity lower than that of Rituximab (HY-P9913). PF-5212374 has antitumor activity and can be used in the research of tumors such as lymphoma and inflammatory diseases.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

  • Reinheit: 97.9%
  • CAS. Nr.: 1169717-01-4
  • Molecular Weight:109.256 kDa
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for PF-5212374
  • PF-5212374 Chemical Structure
    PF-5212374 Chemical Structure
CAS. Nr.: 1169717-01-4
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PF-5212374 Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Finden Sie Ihren Händler vor Ort Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Immobilized CD20/MS4A1 Protein-VLP, Human (HEK293, HY-P78543) can bind PF-5212374 (TRU-015). The EC50 for this effect is 233 ng/mL.

  • PF-5212374 Chemical Structure
    1/16
  • PF-5212374
  • Immobilized CD20/MS4A1 Protein-VLP, Human (HEK293, HY-P78543) can bind PF-5212374 (TRU-015). The EC50 for this effect is 233 ng/mL.