Piperidine-4-sulfonic acid
Based on 1 publication(s) in Google Scholar
Piperidine-4-sulfonic acid is a potent GABA agonist with an IC50 of 0.034 μM for the inhibition of the binding of H-GABA.
For research use only. We do not sell to patients.
- Purity: 99.95%
- CAS No.: 72450-62-5
- Formula: C5H11NO3S
- Molecular Weight:165.21
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) Piperidine-4-sulfonic acid
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Biological Activity
IC50: 0.034 μM (the binding of H-GABA)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Oocyte | EC50 |
20 μM
Compound: 5b
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Effective agonist dose for human Gamma-aminobutyric acid A receptor alpha-5-beta-3-gamma-2 expressed in Xenopus oocytes
Effective agonist dose for human Gamma-aminobutyric acid A receptor alpha-5-beta-3-gamma-2 expressed in Xenopus oocytes
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[PMID: 11412984] |
| Oocyte | EC50 |
26 μM
Compound: 5b
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Agonist activity on human Gamma-aminobutyric acid A receptor alpha-2-beta-3-gamma-2 expressed in Xenopus oocytes
Agonist activity on human Gamma-aminobutyric acid A receptor alpha-2-beta-3-gamma-2 expressed in Xenopus oocytes
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[PMID: 11412984] |
| Oocyte | EC50 |
40 μM
Compound: 5b
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Effective agonist dose for human Gamma-aminobutyric acid A receptor alpha-1-beta-3-gamma-2 expressed in Xenopus oocytes
Effective agonist dose for human Gamma-aminobutyric acid A receptor alpha-1-beta-3-gamma-2 expressed in Xenopus oocytes
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[PMID: 11412984] |
| Oocyte | EC50 |
65 μM
Compound: 5b
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Agonist activity on human Gamma-aminobutyric acid A receptor alpha-3-beta-3-gamma-2 expressed in Xenopus oocytes
Agonist activity on human Gamma-aminobutyric acid A receptor alpha-3-beta-3-gamma-2 expressed in Xenopus oocytes
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[PMID: 11412984] |
Chemical Information
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CAS No. 72450-62-5
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Appearance Solid
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Molecular Weight 165.21
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Formula C5H11NO3S
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Color Off-white to light brown
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SMILES
O=S(C1CCNCC1)(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Nat Commun
2025 Aug 11;16(1):7394. PMID: 40789850
Solvent & Solubility
H2O : 50 mg/mL (302.65 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 6.0529 mL | 30.2645 mL | 60.5290 mL | 151.3226 mL |
| 5 mM | 1.2106 mL | 6.0529 mL | 12.1058 mL | 30.2645 mL | |
| 10 mM | 0.6053 mL | 3.0265 mL | 6.0529 mL | 15.1323 mL | |
| 15 mM | 0.4035 mL | 2.0176 mL | 4.0353 mL | 10.0882 mL | |
| 20 mM | 0.3026 mL | 1.5132 mL | 3.0265 mL | 7.5661 mL | |
| 25 mM | 0.2421 mL | 1.2106 mL | 2.4212 mL | 6.0529 mL | |
| 30 mM | 0.2018 mL | 1.0088 mL | 2.0176 mL | 5.0441 mL | |
| 40 mM | 0.1513 mL | 0.7566 mL | 1.5132 mL | 3.7831 mL | |
| 50 mM | 0.1211 mL | 0.6053 mL | 1.2106 mL | 3.0265 mL | |
| 60 mM | 0.1009 mL | 0.5044 mL | 1.0088 mL | 2.5220 mL | |
| 80 mM | 0.0757 mL | 0.3783 mL | 0.7566 mL | 1.8915 mL | |
| 100 mM | 0.0605 mL | 0.3026 mL | 0.6053 mL | 1.5132 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Piperidine-4-sulfonic acid Related Classifications
HY-139116 Related Classifications
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