PKR-IN-C16 (Standard)
PKR-IN-C16 (Standard) is the analytical standard of PKR-IN-C16 (HY-13977A). This product is intended for research and analytical applications. PKR-IN-C16 (Compound C16) is a specific double-stranded RNA-dependent protein Kinase (PKR) inhibitor. PKR-IN-C16 shows promising neuroprotective properties and can rescue acute brain lesions.
For research use only. We do not sell to patients.
- CAS No.: 608512-97-6
- Formula: C13H8N4OS
- Molecular Weight:268.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 608512-97-6
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Molecular Weight 268.29
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Formula C13H8N4OS
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SMILES
O=C1/C(C2=C(SC=N3)C3=CC=C2N1)=C\C4=CN=CN4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Tronel C, et al. The specific PKR inhibitor C16 prevents apoptosis and IL-1β production in an acute excitotoxic rat model with a neuroinflammatory component. Neurochem Int. 2014 Jan;64:73-83. [Content Brief]
[2]. Page G, et al. Activated double-stranded RNA-dependent protein kinase and neuronal death in models of Alzheimer's disease. Neuroscience. 2006;139(4):1343-54. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)