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Cat. No.: HY-156336

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PLK1-IN-7

PLK1-IN-7 (compound 30e) is a potent PLK1 inhibitor, with an IC₅₀ of 0.66 nM. PLK1-IN-7 exhibits antiproliferative and antitumor activities.

For research use only. We do not sell to patients.

CAS No.: 2938910-96-2
Formula: C₂₄H₂₄F₄N₈O₂
Molecular Weight:532.49

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

PLK1-IN-7 Chemical Structure

CAS No.: 2938910-96-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

PLK1-IN-7 (compound 30e) is a potent PLK1 inhibitor, with an IC₅₀ of 0.66 nM. PLK1-IN-7 exhibits antiproliferative and antitumor activities^[1].

All Polo-like Kinase (PLK) Isoforms :

Chemical Information

CAS No. 2938910-96-2
Molecular Weight 532.49
Formula C₂₄H₂₄F₄N₈O₂
SMILES

FC(F)(OC(C=CC(N1CCN(C)CC1)=C2)=C2NC3=NC=C4C(C5=C(C=C4)C(C(N)=O)=NN5CCF)=N3)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lu J, et, al. Design, synthesis, and biological evaluation of novel molecules as potent inhibitors of PLK1. Bioorg Chem. 2023 Oct:139:106711. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Chemical Information
Purity & Documentation
References

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PLK1-IN-7

All Polo-like Kinase (PLK) Isoforms