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Referencia número: HY-112111A

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Poly-L-Glutamic acid (MW 100000)

Poly-L-Glutamic acid (MW 100000) is a synthetic polypeptide with biocompatibility, biodegradability and non-immunogenicity. Poly-L-Glutamic acid is an ideal tumor-targeting polymer carrier. Poly-L-Glutamic acid can be hydrolyzed by cathepsin B during metabolic decomposition.

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No. CAS: 25513-46-6
Fòrmula: (C₅H₉NO₄)x
Peso molecular:100000 (Average)

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Poly-L-Glutamic acid (MW 100000) Chemical Structure

No. CAS: 25513-46-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

HY-112111
Poly-L-Glutamic acid (MW 700000)

Actividad biológica
- Descripciòn
- In Vitro
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

Ver todos los productos específicos de isoformas Cathepsin :

In Vitro

Poly-L-Glutamic acid acts as a covalent carrier for Paclitaxel (TXL) (HY-B0015) to form PG-TXL (CT-2103)^[1].
Poly-L-Glutamic acid is used to construct targeted hybrid peptosomes co-loaded with Doxorubicin (HY-15142A) and USPIONs as a theranostic platform for metastatic breast cancer^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 25513-46-6
Peso molecular 100000 (Average)
Fòrmula (C₅H₉NO₄)x
SMILES

OC(CC[C@H](N)C(O)=O)=O.[x]
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Singer JW, et al. Poly-(L)-glutamic acid-paclitaxel (CT-2103) [XYOTAX], a biodegradable polymeric drug conjugate: characterization, preclinical pharmacology, and preliminary clinical data. Adv Exp Med Biol. 2003;519:81-99.

[2]. Li C. Poly(L-glutamic acid)--anticancer drug conjugates. Adv Drug Deliv Rev. 2002 Sep 13;54(5):695-713. [Content Brief]

[3]. Hasannia M, et al. Targeted poly(L-glutamic acid)-based hybrid peptosomes co-loaded with doxorubicin and USPIONs as a theranostic platform for metastatic breast cancer. Nanomedicine. 2023 Feb;48:102645. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

Poly-L-Glutamic acid (MW 100000)

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Actividad biológica
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- In Vitro
Chemical Information
Pureza y Documentación
Referencias

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Poly-L-Glutamic acid (MW 100000)

Ver todos los productos específicos de isoformas Cathepsin

Actividad biológica

Descripciòn

In Vitro

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

Poly-L-Glutamic acid (MW 100000) Related Classifications

HY-112111A Related Classifications

Bioz

Keywords

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