Polyoxyethylene (10) lauryl ether
Based on 1 Customer Validation
Polyoxyethylene (10) lauryl ether is a nonionic surfactant. Polyoxyethylene (10) lauryl ether exhibits unique properties in dissolving liposomes and exerts the minimal interference with endotoxin detection. Polyoxyethylene (10) lauryl ether forms hybrid liposomes with Dimyristoylphosphatidylcholine (DMPC) (HY-109541), which can inhibit the proliferation of human promyelocytic leukemia cells without the administration of any drugs.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 9002-92-0
- Formula: C32H66O11
- Molecular Weight:626.86
-
Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Protocols
- Purity & Documentation
- References
-
Help & FAQs
-
HY-P73300
MMP-9 Protein, Human (HEK293) -
HY-B2106
Polidocanol,Hydroxyl Value 40-60 mgKOH/gSclerosing Agent -
HY-Y1883
Polyethylene glycol mono(4-tert-octylphenyl) ether surfactantNonionic Surfactant -
HY-Y1883A
Polyethylene glycol mono(4-tert-octylphenyl) etherNonionic Surfactant -
HY-Y1891
Tween 80 -
HY-141415
Tween 20Nonionic Surfactant -
HY-B2106DR
Polyoxyethylene (10) lauryl ether (Standard)Standard of Polyoxyethylene (10) lauryl ether -
HY-W250168
Polyoxyethylene(10) oleyl etherBiochemical Assay Reagent -
HY-Y0316B
Sodium dodecyl sulfate for electrophoresisBiochemical Assay Reagent -
HY-Y0316
Sodium dodecyl sulfatePharmaceutical Excipient -
HY-N1446C
Sorbitan monooleateEmulsifier -
HY-W127624
Polyoxyethylene monocetyl ether (n=approx. 23)Surfactant
Biological Activity
Description
In Vitro
Polyoxyethylene (10) lauryl ether enhanced the anti-tumor activity of DMPC and its hybrid liposomes activated caspase-3/8/9 and Fas, inducing apoptosis in HL-60 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
-
CAS No. 9002-92-0
-
Appearance Oil
-
Molecular Weight 626.86
-
Formula C32H66O11
-
Color Colorless to off-white
-
SMILES
CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
-
Synonyms
Decaethylene glycol monododecyl ether (C12E10); Polidocanol (10)
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (159.53 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : ≥ 100 mg/mL (159.53 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocols
-
Cell Viability Determination by MTT Colorimetric Assay
The following protocol uses the MTT colorimetric assay as a classic literature-established method for assessing cell viability/metabolic activity in cultured mammalian cells. MTT[3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] is reduced by metabolically active cells to a colored formazan product; the amount of formazan is quantified spectrophotometrically and provides an indirect measure of metabolically active viable cells. Importantly, MTT reduction reflects cellular oxidoreductase/metabolic activity rather than an absolute direct count of living cells, so changes in cellular metabolism can alter the signal independently of cell number.
Purity & Documentation
-
Data Sheet (264 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 1.5953 mL | 7.9763 mL | 15.9525 mL | 39.8813 mL |
| 5 mM | 0.3191 mL | 1.5953 mL | 3.1905 mL | 7.9763 mL | |
| 10 mM | 0.1595 mL | 0.7976 mL | 1.5953 mL | 3.9881 mL | |
| 15 mM | 0.1064 mL | 0.5318 mL | 1.0635 mL | 2.6588 mL | |
| 20 mM | 0.0798 mL | 0.3988 mL | 0.7976 mL | 1.9941 mL | |
| 25 mM | 0.0638 mL | 0.3191 mL | 0.6381 mL | 1.5953 mL | |
| 30 mM | 0.0532 mL | 0.2659 mL | 0.5318 mL | 1.3294 mL | |
| 40 mM | 0.0399 mL | 0.1994 mL | 0.3988 mL | 0.9970 mL | |
| 50 mM | 0.0319 mL | 0.1595 mL | 0.3191 mL | 0.7976 mL | |
| 60 mM | 0.0266 mL | 0.1329 mL | 0.2659 mL | 0.6647 mL | |
| 80 mM | 0.0199 mL | 0.0997 mL | 0.1994 mL | 0.4985 mL | |
| 100 mM | 0.0160 mL | 0.0798 mL | 0.1595 mL | 0.3988 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Polyoxyethylene (10) lauryl ether Related Classifications
HY-B2106D Related Classifications
Powered by Bioz