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Cat. No.: HY-187177

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Pomalidomide-C2-NHCO-C7-NHBoc

Pomalidomide-C2-NHCO-C7-NHBoc is an E3 ligase ligand-linker conjugate, in which the E3 ligase ligand is Thalidomide 4-fluoride (HY-41547). Pomalidomide-C2-NHCO-C7-NHBoc can be conjugated with PARP1 ligand-3 (HY-200661) to synthesize the PARP1 PROTAC degrader CPP-13 (HY-187176).

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CAS No.: 3067348-77-7
Formule: C₂₈H₃₉N₅O₇
Masse moléculaire:557.64

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Please store the product under the recommended conditions in the Certificate of Analysis.

Pomalidomide-C2-NHCO-C7-NHBoc Chemical Structure

CAS No.: 3067348-77-7

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

IC₅₀ & Target^[1]

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Chemical Information

CAS No. 3067348-77-7
Masse moléculaire 557.64
Formule C₂₈H₃₉N₅O₇
SMILES

O=C(NCCNC1=CC=CC2=C1C(N(C2=O)C3CCC(NC3=O)=O)=O)CCCCCCCNC(OC(C)(C)C)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Sun H, et al. Potent and isoform-selective PARP1 degraders for the treatment of BRCA-deficient cancers. Bioorganic chemistry. 2026 Sep 15;180:110204. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Pomalidomide-C2-NHCO-C7-NHBoc

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Pomalidomide-C2-NHCO-C7-NHBoc

Voir tous les produits spécifiques à Isoform E3 Ligase Ligand-Linker Conjugates

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Pomalidomide-C2-NHCO-C7-NHBoc Related Classifications

HY-187177 Related Classifications

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