3067348-77-7
3067348-77-7
Chemical Structure
Pomalidomide-C2-NHCO-C7-NHBoc
- CAS. Nr.: 3067348-77-7
- Formula:C28H39N5O7
- Molecular Weight:557.64
InChIKey: ZGUCNJBYCCNBNK-UHFFFAOYSA-N
SMILES: O=C(NCCNC1=CC=CC2=C1C(N(C2=O)C3CCC(NC3=O)=O)=O)CCCCCCCNC(OC(C)(C)C)=O
Biological Activity: Pomalidomide-C2-NHCO-C7-NHBoc is an E3 ligase ligand-linker conjugate, in which the E3 ligase ligand is Thalidomide 4-fluoride (HY-41547). Pomalidomide-C2-NHCO-C7-NHBoc can be conjugated with PARP1 ligand-3 (HY-200661) to synthesize the PARP1 PROTAC degrader CPP-13 (HY-187176)[1].
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Pomalidomide-C2-NHCO-C7-NHBoc | Pomalidomide-C2-NHCO-C7-NHBoc is an E3 ligase ligand-linker conjugate, in which the E3 ligase ligand is Thalidomide 4-fluoride (HY-41547). Pomalidomide-C2-NHCO-C7-NHBoc can be conjugated with PARP1 ligand-3 (HY-200661) to synthesize the PARP1 PROTAC degrader CPP-13 (HY-187176). | |||||||||||||||||||||
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References
Keywords
