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  3. Poricoic acid G

Poricoic acid G is a triterpenoid that can be isolated from Poria cocos. Poricoic acid G has a significant cytotoxic effect on leukemia cells and is a potential potent anti-leukemic compound in humans.

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Poricoic acid G

Poricoic acid G Estructura química

No. CAS : 415724-84-4

Tamaño Precio Stock Cantidad
1 mg Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
5 mg Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
10 mg Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
50 mg   Obtener un presupuesto  
100 mg   Obtener un presupuesto  
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Descripciòn

Poricoic acid G is a triterpenoid that can be isolated from Poria cocos. Poricoic acid G has a significant cytotoxic effect on leukemia cells and is a potential potent anti-leukemic compound in humans[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
>100 μM
Compound: 3a
Cytotoxicity in human A549 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity in human A549 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 21250700]
AZ-521 cell line IC50
>100 μM
Compound: 3a
Cytotoxicity in human AZ-521 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity in human AZ-521 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 21250700]
DU-145 IC50
>100 μM
Compound: 3a
Cytotoxicity in human DU145 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity in human DU145 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 21250700]
HL-60 GI50
39.3 nM
Compound: 1, poricoic acid G
Growth inhibition of human HL60 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human HL60 cells after 48 hrs by sulforhodamine B assay
[PMID: 11975480]
HL-60 GI50
39.3 nM
Compound: 124
Cytotoxicity against human HL60 cells
Cytotoxicity against human HL60 cells
[PMID: 23092389]
HL-60 GI50
39.3 nM
Compound: 79
Cytotoxicity against human HL60 cells
Cytotoxicity against human HL60 cells
[PMID: 14987072]
HL-60 IC50
32.6 μM
Compound: 14
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
[PMID: 19746919]
HL-60 IC50
32.6 μM
Compound: 3a
Cytotoxicity in human HL60 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity in human HL60 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 21250700]
OVCAR-3 IC50
>100 μM
Compound: 3a
Cytotoxicity in human OVCAR3 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity in human OVCAR3 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 21250700]
PANC-1 IC50
>100 μM
Compound: 3a
Cytotoxicity in human PANC1 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity in human PANC1 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 21250700]
SK-BR-3 IC50
>100 μM
Compound: 3a
Cytotoxicity in human SK-BR-3 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity in human SK-BR-3 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 21250700]
Peso molecular

486.68

Fòrmula

C30H46O5

No. CAS
SMILES

C/C(C)=C\CC[C@@H](C(O)=O)[C@H]1[C@H](O)C[C@]2(C)[C@]1(C)CCC3=C2CC[C@@H](C(C)=C)[C@@]3(CCC(O)=O)C

Structure Classification
Initial Source

Poria cocos

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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Referencias
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nombre del producto:
Poricoic acid G
Cat. No.:
HY-N10071
Cantidad:
MCE Japan Authorized Agent: