Potassium oxonate (Standard)
Potassium oxonate (Standard) is the analytical standard of Potassium oxonate (HY-17511). This product is intended for research and analytical applications. Potassium oxonate (Potassium azaorotate) is a uricase inhibitor that inhibits the phosphorylation of 5-FU to 5-fluorouridine-5'-monophosphate.
For research use only. We do not sell to patients.
- CAS No.: 2207-75-2
- Formula: C4H2KN3O4
- Molecular Weight:195.17
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
CAS No. 2207-75-2
-
Molecular Weight 195.17
-
Formula C4H2KN3O4
-
SMILES
O=C(O[K])C1=NC(O)=NC(O)=N1
-
Synonyms
Potassium azaorotate (Standard); Potassium otastat (Standard); Oteracil potassium (Standard)
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Shirasaka T, et al. Inhibition by oxonic acid of gastrointestinal toxicity of 5-fluorouracil without loss of its antitumor activity in rats. Cancer Res. 1993 Sep 1;53(17):4004-9. [Content Brief]
[2]. Eraranta A, et al. Oxonic acid-induced hyperuricemia elevates plasma aldosterone in experimental renal insufficiency. J Hypertens. 2008 Aug;26(8):1661-8. [Content Brief]
[3]. Yoshisue K, et al. Tissue distribution and biotransformation of potassium oxonate after oral administration of a novel antitumor agent (drug combination of tegafur, 5-chloro-2,4-dihydroxypyridine, and potassium oxonate) to rats. Drug Metab Dispos. 2000 Oct;28(10):1162-7. [Content Brief]
[4]. Chen Y, et al. Curcumin attenuates potassium oxonate-induced hyperuricemia and kidney inflammation in mice. Biomed Pharmacother. 2019 Oct;118:109195. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)