STK38/NDR1
STK38, commonly called NDR1, is one of two NDR kinases that lie outside the Hippo-specific LATS clade. Its activation depends on binding of MOB-family coactivators and on phosphorylation of a hydrophobic-motif serine by an upstream kinase, with autophosphorylation of an activation-loop threonine completing the switch. NDR1 governs centrosome duplication, mitotic entry and apoptosis, and it is activated when caspase cleavage of its MOB1 partner releases autoinhibition during cell death. Unlike LATS1 and LATS2 it is not a principal YAP kinase. Recombinant NDR1 is applied to MOB-dependent activation studies, centrosome biology and NDR/LATS selectivity profiling.
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STK38/NDR1 Recombinant Proteins (1)
- Species:
- Source:
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
