Protonstatin-1
Based on 1 Customer Validation
Protonstatin-1 is a selective plasma membrane (PM) H+-ATPase inhibitor (IC50 of 3.9 μM) that inhibits auxin transport. Protonstatin-1 interacts with the PM H+-ATPase central loop and may thus impede the functions of the N- and/or P-domain to inhibit the pump activity.
For research use only. We do not sell to patients.
- Purity: 98.47%
- CAS No.: 521972-99-6
- Formula: C8H5NO2S2
- Molecular Weight:211.26
-
Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Protonstatin-1 (25 μM) decreases the inhibition of AHA2 activity in yeast strain RS72-AHA2, resulting in decreased yeast cell growth[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 521972-99-6
-
Appearance Solid
-
Molecular Weight 211.26
-
Formula C8H5NO2S2
-
Color Yellow to brown
-
SMILES
O=C1NC(S/C1=C\C2=CC=CO2)=S
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 70 mg/mL (331.35 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (276 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
[1]. Yongqing Yang, et al. Testing the polar auxin transport model with a selective plasma membrane H+ -ATPase inhibitor. J Integr Plant Biol. 2022 Jun;64(6):1229-1245. [Content Brief]
[2]. Yongqing Yang, et al. Screening of protonstatin-1 (PS-1) analogs for improved inhibitors of plant plasma membrane H+-ATPase activity. Front Plant Sci. 2022 Oct 12:13:973471. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.7335 mL | 23.6675 mL | 47.3350 mL | 118.3376 mL |
| 5 mM | 0.9467 mL | 4.7335 mL | 9.4670 mL | 23.6675 mL | |
| 10 mM | 0.4734 mL | 2.3668 mL | 4.7335 mL | 11.8338 mL | |
| 15 mM | 0.3156 mL | 1.5778 mL | 3.1557 mL | 7.8892 mL | |
| 20 mM | 0.2367 mL | 1.1834 mL | 2.3668 mL | 5.9169 mL | |
| 25 mM | 0.1893 mL | 0.9467 mL | 1.8934 mL | 4.7335 mL | |
| 30 mM | 0.1578 mL | 0.7889 mL | 1.5778 mL | 3.9446 mL | |
| 40 mM | 0.1183 mL | 0.5917 mL | 1.1834 mL | 2.9584 mL | |
| 50 mM | 0.0947 mL | 0.4734 mL | 0.9467 mL | 2.3668 mL | |
| 60 mM | 0.0789 mL | 0.3945 mL | 0.7889 mL | 1.9723 mL | |
| 80 mM | 0.0592 mL | 0.2958 mL | 0.5917 mL | 1.4792 mL | |
| 100 mM | 0.0473 mL | 0.2367 mL | 0.4734 mL | 1.1834 mL |
Protonstatin-1 Related Classifications
HY-W317853 Related Classifications
Powered by Bioz