Low-dose IL-2 Ameliorates Experimental Autoimmune Myasthenia Gravis in Rats by Restoring the CD4-positive Helper T-cell Balance Via the JAK/STAT5 Pathway

  • J Neuroimmune Pharmacol. 2026 Jan 31;21(1):9. doi: 10.1007/s11481-025-10276-5.
Shanshan Peng  1 ,  Xiaotong Kong  1 ,  Wenqi Tian  1 ,  Fanfan Xu  1 ,  Hanlu Cai  1 ,  Fei Wu  1 ,  Ying Li  1 ,  Guanghao Xin  1 ,  Jingyan Niu  1 ,  Yingjie Ren  1 ,  Lei Li  1 ,  Jianjian Wang  1 ,  Huixue Zhang  2 ,  Lihua Wang  3
Affiliations
  • 1. Department of Neurology, The Second Affiliated Hospital of Harbin Medical University, Harbin, 150081, China.
  • 2. Department of Neurology, The Second Affiliated Hospital of Harbin Medical University, Harbin, 150081, China. [email protected].
  • 3. The Second Affiliated Hospital of Harbin Medical University, Harbin, 150081, China. [email protected].
PMID: 41619069 DOI: 10.1007/s11481-025-10276-5
Keywords
CD4-positive helper t cell; Experimental autoimmune myasthenia gravis; Low-dose IL-2; Myasthenia gravis; Tfh; Tfr; Th17; Treg.
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