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Ranibizumab (anti-VEGF)

(Synonyms: RG-6321 (anti-VEGF))
2 Cited Publications
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Based on 2 publication(s) in Google Scholar

Ranibizumab (RG-6321) (anti-VEGF) is a humanized anti-VEGF monoclonal antibody fragment and can recognize all VEGF-A isoforms (VEGF110, VEGF121, and VEGF165). Ranibizumab (anti-VEGF) slows vision loss in vivo and is used for wet age-related macular degeneration (AMD) research.

For research use only. We do not sell to patients.

  • Purity : 99.60%
  • CAS No.: 347396-82-1
  • Molecular Weight:49.19 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Ranibizumab (anti-VEGF)
  • Experimental Validation Results for Ranibizumab (anti-VEGF)
  • Experimental Validation Results for Ranibizumab (anti-VEGF)
  • Experimental Validation Results for Ranibizumab (anti-VEGF)
  • Ranibizumab (anti-VEGF) Chemical Structure
    Ranibizumab (anti-VEGF) Chemical Structure
CAS No.: 347396-82-1
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Ranibizumab (anti-VEGF) Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Publications Citing Use of MedChemExpress (MCE) Ranibizumab (anti-VEGF)

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All VEGFR Isoforms

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Assay Types
  • 1/16

    Fab-G1-kappa

  • 1/16

    Immobilized VEGFA-FC can bind Ranibizumab (anti-VEGF). The EC50 for this effect is 10.14 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 Hela cells with Ranibizumab (anti-VEGF) (HY-P9951A, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • 1/16

    Ranibizumab (anti-VEGF) purchased from MedChemExpress. Usage Cited in: Diabetologia. 2025 Jun;68(6):1335-1351. [Abstract]

    Customer Validation
     Retina lysates from db/db mice treated with anti-VEGF (Ranibizumab) (500 ng/mouse; intravitreal injection; single injection into 20-week-old mice) or vehicle (PBS) were analyzed for MAP4K4 expression and activity by immunoblotting. Moesin is a direct substrate of MAP4K4.

  • Ranibizumab (anti-VEGF) Chemical Structure
    1/16
  • Ranibizumab (anti-VEGF)
  • Immobilized VEGFA-FC can bind Ranibizumab (anti-VEGF). The EC50 for this effect is 10.14 ng/mL.
  • Flow cytometric analysis of 1X106 Hela cells with Ranibizumab (anti-VEGF) (HY-P9951A, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Fab-G1-kappa