Rec 15/2615 hydrochloride
Rec 15/2615 hydrochloride is a potent and selective α-1B adrenoceptor antagonist with Ki values of 1.9 nM, 0.3 nM, 2.6 nM for α1A, α1B, α1D, respectively. Rec 15/2615 hydrochloride modulates vaginal smooth muscle contractility and genital engorgement.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 173059-17-1
- Formel: C26H34ClN5O5
- Molecular Weight:532.03
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Alle Adrenergic Receptor Isoform-spezifische Produkte anzeigen
More
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
α1A-adrenergic receptor 1.9 nM (Ki) |
α1B-adrenergic receptor 0.3 nM (Ki) |
Alpha-1D adrenergic receptor 2.6 nM (Ki) |
Chemical Information
-
CAS. Nr. 173059-17-1
-
Molecular Weight 532.03
-
Formel C26H34ClN5O5
-
SMILES
CC(C1=C(OCC(N2CCN(C3=NC(N)=C4C=C(OC)C(OC)=CC4=N3)CC2)=O)C(OC)=CC=C1)C.[H]Cl
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Bremner JB, et al. Ligand design for alpha1 adrenoceptor subtype selective antagonists. Bioorg Med Chem. 2000 Jan;8(1):201-14. [Content Brief]
[2]. Kim NN, et al. Biochemical and functional characterization of alpha-adrenergic receptors in the rabbit vagina. Life Sci. 2002 Nov 1;71(24):2909-20. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Rec 15/2615 hydrochloride Related Classifications
HY-103209 Related Classifications
Powered by Bioz