Rec 15/2615 hydrochloride
Rec 15/2615 hydrochloride is a potent and selective α-1B adrenoceptor antagonist with Ki values of 1.9 nM, 0.3 nM, 2.6 nM for α1A, α1B, α1D, respectively. Rec 15/2615 hydrochloride modulates vaginal smooth muscle contractility and genital engorgement.
For research use only. We do not sell to patients.
- CAS No.: 173059-17-1
- Formula: C26H34ClN5O5
- Molecular Weight:532.03
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Adrenergic Receptor Isoforms
More
Biological Activity
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α1A-adrenergic receptor 1.9 nM (Ki) |
α1B-adrenergic receptor 0.3 nM (Ki) |
Alpha-1D adrenergic receptor 2.6 nM (Ki) |
Chemical Information
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CAS No. 173059-17-1
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Molecular Weight 532.03
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Formula C26H34ClN5O5
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SMILES
CC(C1=C(OCC(N2CCN(C3=NC(N)=C4C=C(OC)C(OC)=CC4=N3)CC2)=O)C(OC)=CC=C1)C.[H]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Bremner JB, et al. Ligand design for alpha1 adrenoceptor subtype selective antagonists. Bioorg Med Chem. 2000 Jan;8(1):201-14. [Content Brief]
[2]. Kim NN, et al. Biochemical and functional characterization of alpha-adrenergic receptors in the rabbit vagina. Life Sci. 2002 Nov 1;71(24):2909-20. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Rec 15/2615 hydrochloride Related Classifications
HY-103209 Related Classifications
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