CEACAM1 Protein, Human (His-SUMO)
CEACAM1 protein is involved in various biological processes. It is phosphorylated by the insulin receptor (INSR) in response to insulin stimulation, thereby promoting insulin clearance and regulating hepatic lipogenesis. CEACAM1 Protein, Human (His-SUMO) is the recombinant human-derived CEACAM1 protein, expressed by E. coli , with N-10*His, N-SUMO labeled tag.
- Species: Human
- Source: E. coli
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
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Biological Activity
Description
CEACAM1 protein is involved in various biological processes. It is phosphorylated by the insulin receptor (INSR) in response to insulin stimulation, thereby promoting insulin clearance and regulating hepatic lipogenesis. CEACAM1 Protein, Human (His-SUMO) is the recombinant human-derived CEACAM1 protein, expressed by E. coli , with N-10*His, N-SUMO labeled tag.
Background
The SF3R gene is involved in various biological processes and functions. It regulates insulin action by promoting the clearance of insulin and regulating lipogenesis in the liver. Upon insulin stimulation, SF3R undergoes phosphorylation by the insulin receptor (INSR), leading to increased insulin endocytosis and degradation. This results in a reduction of fatty acid synthesis. SF3R also plays a role in down-regulating cell proliferation through its interaction with SHC1, which decreases the coupling of SHC1 to the MAPK3/ERK1-MAPK1/ERK2 and phosphatidylinositol 3-kinase pathways.
Technical Parameters
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Species Human
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Source E. coli
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Tag N-10*His;N-SUMO
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Accession
P13688-1 (Q35-G428)
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Molecular Construction
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N-term
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10*His-SUMO
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CEACAM1 (Q35-G428)
Accession # P13688-1 -
C-term
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Protein Length
Extracellular Domain
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Synonyms
CEACAM1; CD66a; Prev. BGP; Biliary Glycoprotein 1; BGP1; CEACAM1 Protein; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein); Antigen CD66; Carcinoembryonic Antigen Related Cell Adhesion Molecule 1; BGP-1; Cell Adhesion Molec
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AA Sequence
QLTTESMPFNVAEGKEVLLLVHNLPQQLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPG
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Predicted Molecular Mass
63.3 kDa
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US;may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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