PDGF-AB Protein, Human (Solution)
Based on 1 Customer Validation
PDGF-A protein is a key growth factor regulating embryonic development, cell proliferation, migration, survival, and chemotaxis, and effectively promotes mitosis in mesenchymal cells. PDGF-B protein is a key growth factor that centrally regulates embryonic development, cell proliferation, migration, survival, and chemotaxis. PDGF-AB Protein, Human (Solution) is a recombinant PDGF-AB protein expressed by E.coli without a tag.
- Species: Human
- Source: E. coli
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Biological Activity
PDGF-A protein is a key growth factor regulating embryonic development, cell proliferation, migration, survival, and chemotaxis, and effectively promotes mitosis in mesenchymal cells. PDGF-B protein is a key growth factor that centrally regulates embryonic development, cell proliferation, migration, survival, and chemotaxis. PDGF-AB Protein, Human (Solution) is a recombinant PDGF-AB protein expressed by E.coli without a tag.
PDGF-A protein plays a central role as a key growth factor regulating embryonic development, cell proliferation, migration, survival, and chemotaxis. PDGF-A is renowned for its effective mitotic-promoting effect on mesenchymal cells and is indispensable for various developmental processes, including alveolar septum formation, gastrointestinal development, Leydig cell maturation, spermatogenesis, and normal oligodendrocyte development, contributing to myelination of oligodendrocytes in the spinal cord and cerebellum. Furthermore, PDGF-A plays a crucial role in wound healing dynamics. PDGF-B protein is a key member of the PDGF/VEGF growth factor family, indicating its crucial role in cell signaling and tissue development. As part of this growth factor family, PDGF-B may share conserved structural and functional features with related proteins, contributing to cell growth, angiogenesis, and vascular development.
Technical Parameters
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Species Human
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Source E. coli
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Tag Tag Free
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Accession
P04085 (S87-T211)&P01127 (S82-T190)
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Gene ID5154&5155
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Molecular Construction
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N-term
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PDGFA (S87-T211)
Accession # P04085 -
C-term
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N-term
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PDGFB (S82-T190)
Accession # P01127 -
C-term
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Synonyms
PDGFAB; PDGF-AB
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Predicted Molecular Mass
14.1 kDa & 12.4 kDa
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Molecular Weight
Approximately 14-20 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Solution
Supplied as a 0.22 μm filtered solution of 4mM HCl.
<0.1 EU/μg, determined by LAL method.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
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Data Sheet (231 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)