PDGF-AB Protein, Human (Solution)

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PDGF-A protein is a key growth factor regulating embryonic development, cell proliferation, migration, survival, and chemotaxis, and effectively promotes mitosis in mesenchymal cells. PDGF-B protein is a key growth factor that centrally regulates embryonic development, cell proliferation, migration, survival, and chemotaxis. PDGF-AB Protein, Human (Solution) is a recombinant PDGF-AB protein expressed by E.coli without a tag.

For research use only. We do not sell to patients.
  • Species: Human
  • Source: E. coli
  • Storage:
    Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
  • Biological Activity
  • Technical Parameters
  • Product Properties
  • Documentation
  • Help & FAQs

Biological Activity

Description

PDGF-A protein is a key growth factor regulating embryonic development, cell proliferation, migration, survival, and chemotaxis, and effectively promotes mitosis in mesenchymal cells. PDGF-B protein is a key growth factor that centrally regulates embryonic development, cell proliferation, migration, survival, and chemotaxis. PDGF-AB Protein, Human (Solution) is a recombinant PDGF-AB protein expressed by E.coli without a tag.

Background

PDGF-A protein plays a central role as a key growth factor regulating embryonic development, cell proliferation, migration, survival, and chemotaxis. PDGF-A is renowned for its effective mitotic-promoting effect on mesenchymal cells and is indispensable for various developmental processes, including alveolar septum formation, gastrointestinal development, Leydig cell maturation, spermatogenesis, and normal oligodendrocyte development, contributing to myelination of oligodendrocytes in the spinal cord and cerebellum. Furthermore, PDGF-A plays a crucial role in wound healing dynamics. PDGF-B protein is a key member of the PDGF/VEGF growth factor family, indicating its crucial role in cell signaling and tissue development. As part of this growth factor family, PDGF-B may share conserved structural and functional features with related proteins, contributing to cell growth, angiogenesis, and vascular development.

Technical Parameters

  • Species Human
  • Source E. coli
  • Tag Tag Free
  • Accession
  • Gene ID
  • Molecular Construction
    • N-term
    • PDGFA (S87-T211)
      Accession # P04085
    • C-term
    • N-term
    • PDGFB (S82-T190)
      Accession # P01127
    • C-term
  • Synonyms

    PDGFAB; PDGF-AB

  • Predicted Molecular Mass

    14.1 kDa & 12.4 kDa

  • Molecular Weight

    Approximately 14-20 kDa, based on SDS-PAGE under reducing conditions.

  • Purity

    ≥ 95%, as determined by reducing SDS-PAGE.

Product Properties

Appearance

Solution

Formulation

Supplied as a 0.22 μm filtered solution of 4mM HCl.

Endotoxin Level

<0.1 EU/μg, determined by LAL method.

Storage & Stability

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Calculators

Reconstitution Calculator

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) Volume (to add to vial)
=
Mass (in vial) Mass (in vial)
÷
Desired Reconstitution Concentration Desired Reconstitution Concentration
Dilution Calculator

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

Concentration (start) Concentration (start)
×
Volume (start) Volume (start)
=
Concentration (final) Concentration (final)
×
Volume (final) Volume (final)
The Specific Activity Calculator Equation
  • Specific Activity (Unit/mg)
  • Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) Specific Activity (Unit/mg)
Unit/mg
= 106 ÷
Biological Activity (ED50) Biological Activity (ED50)
106 ÷
ng/mL
MOQ
Minimum order quantity
100 mg

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