PDGF-B
Encoded by the PDGFB gene, PDGF-B is the chain whose cellular homolog is the simian sarcoma virus v-sis oncogene. It dimerizes as PDGF-BB or heterodimerizes with the A chain and is unique in activating both PDGFR-alpha and PDGFR-beta. A glycosaminoglycan-binding retention motif anchors much of the secreted PDGF-BB near its site of production, enabling localized pericyte and smooth-muscle cell recruitment during angiogenesis and organ development. PDGFB or PDGFRB mutations cause infantile myofibromatosis and familial gliomatosis. Recombinant PDGF-B protein, widely used as a chemoattractant and mitogen, supports vascular biology, wound-healing, and pericyte-related research.
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PDGF-B Recombinant Proteins (5)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
