SAA2/Serum Amyloid A-2 Protein, Mouse (His)

SAA2/Serum Amyloid A-2 Protein, Mouse (His) is the recombinant human-derived SAA2 protein, expressed by E. coli, with N-6*His labeled tag.

For research use only. We do not sell to patients.
  • Species: Mouse
  • Source: E. coli
  • Storage:
    Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
  • Biological Activity
  • Technical Parameters
  • Product Properties
  • Help & FAQs

Biological Activity

Description

SAA2/Serum Amyloid A-2 Protein, Mouse (His) is the recombinant human-derived SAA2 protein, expressed by E. coli, with N-6*His labeled tag.

Background

Serum amyloid A (SAA) is a family of high-density lipoprotein (HDL) related apolipoproteins in plasma, with three subtypes, SAA1, SAA2, and SAA3. SAA2 is mainly expressed and induced in the liver, and the SAA2 gene is regulated by pro-inflammatory factors IL-1, IL-6 and TNF-α. SAA2 is a major acute-phase protein that is highly expressed in inflammatory and tissue injury responses. SAA2 also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of SAA2 have been linked to chronic inflammatory diseases, including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. SAA2 may also be a potential biomarker for certain tumors[1][2][3][4].

Technical Parameters

  • Species Mouse
  • Source E. coli
  • Tag N-6*His
  • Accession
  • Gene ID
  • Molecular Construction
    • N-term
    • 6*His
    • SAA2 (G20-Y122)
      Accession # P05367
    • C-term
  • Protein Length

    Full Length of SAA2 Chain

  • Synonyms

    SAA2; Alternative Protein SAA2; Serum Amyloid A2; Serum Amyloid A Protein; Serum Amyloid A-2 Protein; SAA

  • AA Sequence

    GFFSFIGEAFQGAGDMWRAYTDMKEAGWKDGDKYFHARGNYDAAQRGPGGVWAAEKISDARESFQEFFGRGHEDTMADQEANRHGRSGKDPNYYRPPGLPAKY

  • Predicted Molecular Mass

    15.6 kDa

  • Purity

    ≥ 90%, as determined by reducing SDS-PAGE.

Product Properties

Appearance

Lyophilized powder

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

Storage & Stability

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Calculators

Reconstitution Calculator

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) Volume (to add to vial)
=
Mass (in vial) Mass (in vial)
÷
Desired Reconstitution Concentration Desired Reconstitution Concentration
Dilution Calculator

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

Concentration (start) Concentration (start)
×
Volume (start) Volume (start)
=
Concentration (final) Concentration (final)
×
Volume (final) Volume (final)
The Specific Activity Calculator Equation
  • Specific Activity (Unit/mg)
  • Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) Specific Activity (Unit/mg)
Unit/mg
= 106 ÷
Biological Activity (ED50) Biological Activity (ED50)
106 ÷
ng/mL
MOQ
Minimum order quantity
100 mg

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