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  4. SAA2/Serum Amyloid A-2 Protein, Mouse (His)

SAA2/Serum Amyloid A-2 Protein, Mouse (His) is the recombinant human-derived SAA2 protein, expressed by E. coli, with N-6*His labeled tag.

For research use only. We do not sell to patients.

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Description

SAA2/Serum Amyloid A-2 Protein, Mouse (His) is the recombinant human-derived SAA2 protein, expressed by E. coli, with N-6*His labeled tag.
Background

Serum amyloid A (SAA) is a family of high-density lipoprotein (HDL) related apolipoproteins in plasma, with three subtypes, SAA1, SAA2, and SAA3. SAA2 is mainly expressed and induced in the liver, and the SAA2 gene is regulated by pro-inflammatory factors IL-1, IL-6 and TNF-α. SAA2 is a major acute-phase protein that is highly expressed in inflammatory and tissue injury responses. SAA2 also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of SAA2 have been linked to chronic inflammatory diseases, including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. SAA2 may also be a potential biomarker for certain tumors[1][2][3][4].
Species

Mouse
Source

E. coli
Tag

N-6*His
Accession

P05367 (G20-Y122)
Gene ID

6289
Molecular Construction
N-term
6*His
SAA2 (G20-Y122)
Accession # P05367
C-term
Protein Length

Full Length of Mature Protein
Synonyms
SAA; SAA2; Serum Amyloid A2
AA Sequence

GFFSFIGEAFQGAGDMWRAYTDMKEAGWKDGDKYFHARGNYDAAQRGPGGVWAAEKISDARESFQEFFGRGHEDTMADQEANRHGRSGKDPNYYRPPGLPAKY

Predicted Molecular Mass
15.6 kDa
Purity

≥ 90%, as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

SAA2/Serum Amyloid A-2 Protein, Mouse (His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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SAA2/Serum Amyloid A-2 Protein, Mouse (His)
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