2. Recombinant Proteins
  3. Enzymes & Regulators
  4. Protease Inhibitors
  5. Serpin (Protease Inhibitor)
  6. PAI-1
  7. Serpin E1 Protein, Rat (HEK293, Fc)

Serpin E1 Protein, Rat (HEK293, Fc)

Cat. No.: HY-P73336
Handling Instructions

Serpin E1 is a serine protease inhibitor that regulates TMPRSS7 and inhibits tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). It can significantly downregulate fibrinolysis and control thrombus degradation. Serpin E1 Protein, Rat (HEK293, Fc) is the recombinant rat-derived Serpin E1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Serpin E1 Protein, Rat (HEK293, Fc) is 402 a.a., with molecular weight of ~70 kDa.

For research use only. We do not sell to patients.

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Description

Serpin E1 is a serine protease inhibitor that regulates TMPRSS7 and inhibits tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). It can significantly downregulate fibrinolysis and control thrombus degradation. Serpin E1 Protein, Rat (HEK293, Fc) is the recombinant rat-derived Serpin E1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Serpin E1 Protein, Rat (HEK293, Fc) is 402 a.a., with molecular weight of ~70 kDa.
Background

The SLAMF6 protein is a self-ligand receptor belonging to the signaling lymphocytic activation molecule (SLAM) family. It is involved in modulating the activation and differentiation of various immune cells, playing a role in both innate and adaptive immune responses. The activity of SLAMF6 is regulated by the presence or absence of cytoplasmic adapter proteins, namely SH2D1A/SAP and/or SH2D1B/EAT-2.
Species

Rat
Source

HEK293
Tag

C-hFc
Accession

P20961 (M1-P402)
Gene ID
Molecular Construction
N-term
Serpin E1 (M1-P402)
Accession # P20961
hFc
C-term
Synonyms
Plasminogen activator inhibitor 1; PAI-1; Serpin E1; Serpine1; Planh1
Molecular Weight

Approximately 70 kDa
Purity

Greater than 90% as determined by reducing SDS-PAGE
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

Serpin E1 Protein, Rat (HEK293, Fc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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