Rhizopodin
Rhizopodin is a new cytostatic compound isolated from the culture fluid of the slime mold Myxococcus stipitatus. Rhizopodin inhibits the growth of various animal cell cultures without killing the cells, with an ID50 value of 12 to 30 ng/ml, depending on the cell line. In particular, fibroblast-like cells show typical morphological changes, with cells becoming larger and forming long branched reticular extensions within hours, and these morphological changes are irreversible. Rhizopodin inhibits bleb formation in K-562 cells, possibly through interaction with protein phosphorylation.
For research use only. We do not sell to patients.
- CAS No.: 150346-23-9
- Formula: C78H124N4O22
- Molecular Weight:1469.83
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 150346-23-9
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Molecular Weight 1469.83
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Formula C78H124N4O22
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SMILES
CO[C@]1([H])C2=COC(C[C@@H](C(C)([C@@H](OC(C[C@H](C[C@H](/C=C/C=C/C[C@@](OC)([H])C3=COC(C[C@H](O)C(C)(C)[C@H](C[C@H](OC)[C@@H](C)CCC([C@H](C)[C@H](OC)C/C=C/N(C)C=O)=O)OC(C[C@@H](O)C[C@@H](OC)/C=C/C=C/C1)=O)=N3)OC)O)=O)C[C@H](OC)[C@@H](C)CCC([C@H](C)[C@H](OC)C/C=C/N(C)C=O)=O)C)O)=N2
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Structure Classification
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Initial Source
Myxococcus stipitatus
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)