RO3201195
Based on 1 Customer Validation
RO3201195 (compound 1) is an inhibitor of p38 MAPK. RO3201195 inhibits WS cell proliferation with IC50 value of 190 nM.
For research use only. We do not sell to patients.
- Purity: 99.77%
- CAS No.: 249937-52-8
- Formula: C19H18FN3O4
- Molecular Weight:371.36
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 249937-52-8
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Appearance Solid
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Molecular Weight 371.36
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Formula C19H18FN3O4
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Color White to off-white
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SMILES
O=C(C1=CC=CC(OCC(CO)O)=C1)C2=C(N(N=C2)C3=CC=C(C=C3)F)N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (134.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6928 mL | 13.4640 mL | 26.9280 mL | 67.3201 mL |
| 5 mM | 0.5386 mL | 2.6928 mL | 5.3856 mL | 13.4640 mL | |
| 10 mM | 0.2693 mL | 1.3464 mL | 2.6928 mL | 6.7320 mL | |
| 15 mM | 0.1795 mL | 0.8976 mL | 1.7952 mL | 4.4880 mL | |
| 20 mM | 0.1346 mL | 0.6732 mL | 1.3464 mL | 3.3660 mL | |
| 25 mM | 0.1077 mL | 0.5386 mL | 1.0771 mL | 2.6928 mL | |
| 30 mM | 0.0898 mL | 0.4488 mL | 0.8976 mL | 2.2440 mL | |
| 40 mM | 0.0673 mL | 0.3366 mL | 0.6732 mL | 1.6830 mL | |
| 50 mM | 0.0539 mL | 0.2693 mL | 0.5386 mL | 1.3464 mL | |
| 60 mM | 0.0449 mL | 0.2244 mL | 0.4488 mL | 1.1220 mL | |
| 80 mM | 0.0337 mL | 0.1683 mL | 0.3366 mL | 0.8415 mL | |
| 100 mM | 0.0269 mL | 0.1346 mL | 0.2693 mL | 0.6732 mL |