2. Cell Cycle/DNA Damage TGF-beta/Smad Stem Cell/Wnt Cytoskeleton
  3. ROCK
  4. ROCK2-IN-15

ROCK2-IN-15 (2-11) is a ROCK2 inhibitor with selective activity against Rho-kinase mediated phosphorylation of myosin light chain phosphates .ROCK2-IN-15 can be used for the research of cardiovascular diseases, pulmonary diseases, inflammatory diseases, neurological diseases, proliferative diseases .

For research use only. We do not sell to patients.

ROCK2-IN-15

ROCK2-IN-15 Chemical Structure

CAS No. : 3060005-08-2

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ROCK2-IN-15 Related Antibodies

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Description

ROCK2-IN-15 (2-11) is a ROCK2 inhibitor with selective activity against Rho-kinase mediated phosphorylation of myosin light chain phosphates .ROCK2-IN-15 can be used for the research of cardiovascular diseases, pulmonary diseases, inflammatory diseases, neurological diseases, proliferative diseases [1].

IC50 & Target[1]

ROCK2

 

In Vitro

ROCK2 is a serine/threonine kinase downstream of RhoA that regulates cytoskeleton contraction, immunity and fibrosis, and serves as a key target for autoimmune, fibrotic and neurological diseases.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

ROCK2-IN-15 Related Antibodies
Molecular Weight

407.39

Formula

C22H18FN3O4
CAS No.
SMILES

O=C(C1OC2=CC=C(C=C2OC1)F)C3=CN(CCO)C4=CC(C5=CNN=C5)=CC=C34
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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ROCK2-IN-15 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ROCK2-IN-153060005-08-2ROCKRho-associated protein kinaseRho-associated kinaseRho-kinaseROKproliferative diseasespulmonary diseasescardiovascular diseasesneurological diseasesROCK2myosin light chain phosphatesinflammatory diseasesInhibitorinhibitorinhibit

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