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Cat. No.: HY-123435

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RWJ 22108

RWJ 22108 is a bronchoselective calcium channel blocker, with the IC₅₀ of 5.7 nM in calcium-dependent contraction of canine bronchiolar smooth muscle.

For research use only. We do not sell to patients.

CAS No.: 112769-37-6
Formula: C₂₇H₃₀ClFN₂O₄S
Molecular Weight:533.05

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

RWJ 22108 Chemical Structure

CAS No.: 112769-37-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

RWJ 22108 is a bronchoselective calcium channel blocker, with the IC₅₀ of 5.7 nM in calcium-dependent contraction of canine bronchiolar smooth muscle^[1].

All Calcium Channel Isoforms :

Chemical Information

CAS No. 112769-37-6
Molecular Weight 533.05
Formula C₂₇H₃₀ClFN₂O₄S
SMILES

O=C(OCCN(CC1=CC=CC=C1)C)C2=C(NC(CCCC3)=C(C2C4=C(C=CC=C4Cl)F)S3(=O)=O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. J B Moore Jr, et al. RWJ-22108--a novel airway tissue--selective calcium channel blocker. Agents Actions. 1993 Sep;40(1-2):57-61. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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RWJ 22108

All Calcium Channel Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

RWJ 22108 Related Classifications

HY-123435 Related Classifications