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Cat. No.: HY-123142

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RX809055AX

RX 809055AX is a potent long lasting opioid antagonist with selectivity towards at mu and delta receptors.

For research use only. We do not sell to patients.

CAS No.: 122566-12-5
Formula: C₂₉H₂₉ClN₂O₄
Molecular Weight:505.00

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

RX809055AX Chemical Structure

CAS No.: 122566-12-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

RX 809055AX is a potent long lasting opioid antagonist with selectivity towards at mu and delta receptors^[1].

IC₅₀ & Target

μ Opioid Receptor/MOR

δ Opioid Receptor/DOR

All Opioid Receptor Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
CHO	IC₅₀	0.1 nM Compound: 4a, C-CAM	Activity at human recombinant kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding Activity at human recombinant kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding	[PMID: 17004724]
CHO	IC₅₀	0.19 nM Compound: 4a, C-CAM	Activity at human recombinant delta opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding Activity at human recombinant delta opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding	[PMID: 17004724]
CHO	IC₅₀	0.53 nM Compound: 4a, C-CAM	Activity at human recombinant mu opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding Activity at human recombinant mu opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding	[PMID: 17004724]

Chemical Information

CAS No. 122566-12-5
Molecular Weight 505.00
Formula C₂₉H₂₉ClN₂O₄
SMILES

ClC(C=C1)=CC=C1/C=C/C(N[C@]23[C@@]45C6=C(C[C@@]3([H])N(CC5)CC7CC7)C=CC(O)=C6O[C@@]4([H])C(CC2)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lemcke PK, Ayres EA, Kramer TH, Burks TF. RX809055AX in vivo: a long lasting opioid antagonist at mu and delta receptors. Proc West Pharmacol Soc. 1989;32:173-5. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Amount: USD 0.00

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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RX809055AX

All Opioid Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

RX809055AX Related Classifications

HY-123142 Related Classifications