S-Adenosyl-3-thiopropylamine
Based on 1 Customer Validation
S-Adenosyl-3-thiopropylamine acts as a weak to moderate reversible inhibitor of spermidine/spermine synthase, and its inhibitory activity increases after oxidation (to S-Adenosyl-3-thiopropylamine sulphoxide and S-Adenosyl-3-thiopropylamine sulphone).
For research use only. We do not sell to patients.
- Purity : 98.14%
- CAS No.: 53186-57-5
- Formula: C13H20N6O3S
- Molecular Weight:340.40
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
In Vitro
S-Adenosyl-3-thiopropylamine (0.1-1 mM; 30 min) inhibits purified rat ventral prostate spermidine synthase (55% inhibition at 1 mM) and spermine synthase (65% inhibition at 1 mM), with weak activity at 0.1 mM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 53186-57-5
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Appearance Solid
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Molecular Weight 340.40
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Formula C13H20N6O3S
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Color White to off-white
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SMILES
NCCCSC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C3=NC=NC(N)=C3N=C2)O1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (268 KB)
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SDS (420 KB)
- English - EN (420 KB)
- Français - FR (420 KB)
- Deutsch - DE (420 KB)
- Norwegian - NO (420 KB)
- Español - ES (420 KB)
- Swedish - SV (420 KB)
- Italian - IT (420 KB)
- Korean - KR (420 KB)
- Portuguese - PT (420 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)