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Cat. No.: HY-103608R

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(S,R,S)-AHPC-(C3-PEG)2-C6-Cl (Standard)

Name: (S,R,S)-AHPC-(C3-PEG)2-C6-Cl (Standard)
Brand: MedChemExpress
SKU: HY-103608R
Availability: PreOrder

(Synonyms: VHL Ligand-Linker Conjugates 11 (Standard); E3 ligase Ligand-Linker Conjugates 11 (Standard))

(S,R,S)-AHPC-(C3-PEG)2-C6-Cl (Standard) is the analytical standard of (S,R,S)-AHPC-(C3-PEG)2-C6-Cl (HY-103608). This product is intended for research and analytical applications. (S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-(C3-PEG)2-C6-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays.

For research use only. We do not sell to patients.

CAS No.: 1835705-61-7
Formula: C₃₉H₆₁ClN₄O₆S
Molecular Weight:749.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

(S,R,S)-AHPC-(C3-PEG)2-C6-Cl (Standard) Chemical Structure

CAS No.: 1835705-61-7

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Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 1835705-61-7
Molecular Weight 749.44
Formula C₃₉H₆₁ClN₄O₆S
SMILES

O=C(N[C@@H](C(C)(C)C)C(N(C[C@H](O)C1)[C@@H]1C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)=O)CCCCCOCCCCCOCCCCCCCl
Synonyms

VHL Ligand-Linker Conjugates 11 (Standard); E3 ligase Ligand-Linker Conjugates 11 (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Ashton C. Lai, et al. Modular PROTAC Design for the Degradation of Oncogenic BCR-ABL. Angew Chem Int Ed Engl. 2016 Jan 11; 55(2): 807–810. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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(S,R,S)-AHPC-(C3-PEG)2-C6-Cl (Standard)

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(S,R,S)-AHPC-(C3-PEG)2-C6-Cl (Standard)

(S,R,S)-AHPC-PEG1-N3

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(S,R,S)-AHPC-PEG2-NH2 hydrochloride

(S,R,S)-AHPC-PEG4-NH2 hydrochloride

(S,R,S)-AHPC-PEG4-N3

(S,R,S)-AHPC-PEG6-C4-Cl