1835705-61-7
Chemical Structure
(S,R,S)-AHPC-(C3-PEG)2-C6-Cl
Synonym(s): VHL Ligand-Linker Conjugates 11; E3 ligase Ligand-Linker Conjugates 11
- CAS No.: 1835705-61-7
- Formula:C39H61ClN4O6S
- Molecular Weight:749.44
IUPAC Name: (2S,4R)-1-((S)-2-(6-((5-((6-chlorohexyl)oxy)pentyl)oxy)hexanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
InChIKey: DVLICOWBWULAJJ-RWTOGVPBSA-N
SMILES: O=C(N[C@@H](C(C)(C)C)C(N(C[C@H](O)C1)[C@@H]1C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)=O)CCCCCOCCCCCOCCCCCCCl
Biological Activity: (S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-(C3-PEG)2-C6-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(S,R,S)-AHPC-(C3-PEG)2-C6-Cl | 98.71% | (S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-(C3-PEG)2-C6-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays. | ||||||||||||||||||||
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(S,R,S)-AHPC-(C3-PEG)2-C6-Cl (Standard) | ≥98% | (S,R,S)-AHPC-(C3-PEG)2-C6-Cl (Standard) is the analytical standard of (S,R,S)-AHPC-(C3-PEG)2-C6-Cl (HY-103608). This product is intended for research and analytical applications. (S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-(C3-PEG)2-C6-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays. | ||||||||||||||||||||
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Similarity Score 0.92
HY-103605R(S,R,S)-AHPC-C6-PEG3-C4-Cl (Standard) -
Similarity Score 0.89
HY-W998298(S,R,S)-AHPC-C5-PEG3-C3 -
Similarity Score 0.86
HY-151791(S,R,S)-AHPC-C6-PEG3-butyl-N3 -
Similarity Score 0.84
HY-103607(S,R,S)-AHPC-PEG2-C4-Cl -
Similarity Score 0.83
HY-179230E3 Ligase Ligand-linker Conjugate 214 -
Similarity Score 0.83
HY-129941A(S,R,S)-AHPC-C10-NH2 dihydrochloride -
Similarity Score 0.83
HY-129941(S,R,S)-AHPC-C10-NH2 -
Similarity Score 0.82
HY-163208VH 032 amide-alkylC9-amine hydrochloride -
Similarity Score 0.82
HY-160555A(S,R,S)-AHPC-CO-C9-NH2 hydrochloride -
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