2. Anti-infection
  3. Antibiotic Bacterial
  4. Saquayamycin D

Saquayamycin D is an antibiotic, which can be isolated from Streptomyces nodosus culture broth. Saquayamycin D exhibits antibacterial activity against various gram-positive bacteria with MIC of 12.5-50 μg/mL. Saquayamycin D inhibits the proliferation of Doxorubicin (HY-15142)-sensitive P388/S and Doxorubicin-resistant P388/ADR with IC50 of 0.15 and 0.15 μg/mL.

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Saquayamycin D

Saquayamycin D Chemische Struktur

CAS. Nr. : 99260-71-6

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Beschreibung

Saquayamycin D is an antibiotic, which can be isolated from Streptomyces nodosus culture broth. Saquayamycin D exhibits antibacterial activity against various gram-positive bacteria with MIC of 12.5-50 μg/mL. Saquayamycin D inhibits the proliferation of Doxorubicin (HY-15142)-sensitive P388/S and Doxorubicin-resistant P388/ADR with IC50 of 0.15 and 0.15 μg/mL[1].

Molekulargewicht

822.85

Formel

C43H50O16
CAS. Nr.
SMILES

O=C1C[C@@](O[C@H]2CC[C@H](O[C@H]3CCC([C@H](C)O3)=O)[C@H](C)O2)(C)C[C@]4(O)[C@@]1(O)C(C(C5=CC=C([C@H]6C[C@@]7([H])O[C@](CC([C@H](C)O8)=O)([H])[C@]8([H])O[C@]7([H])[C@@H](C)O6)C(O)=C5C9=O)=O)=C9C=C4
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Room temperature in continental US; may vary elsewhere.
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Saquayamycin D Related Classifications

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Saquayamycin D99260-71-6AntibioticBacterialStreptomyces nodosusantibacterialStaphylococcus aureusMicrococcus lysodeikticusBacillus subtilisEscherichia coliSalmonella typhiSerratia marcescensPseudomonas aeruginosaMycobacterium smegmatisInhibitorinhibitorinhibit

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