Saquayamycins, new aquayamycin-group antibiotics

  • J Antibiot (Tokyo). 1985 Sep;38(9):1171-81. doi: 10.7164/antibiotics.38.1171.
T Uchida ,  M Imoto ,  Y Watanabe ,  K Miura ,  T Dobashi ,  N Matsuda ,  T Sawa ,  H Naganawa ,  M Hamada ,  T Takeuchi
PMID: 3840796 DOI: 10.7164/antibiotics.38.1171
Abstract

From the culture broth of Streptomyces nodosus MH190-16F3, four new Antibiotics have been isolated, and named saquayamycins A, B, C and D. The compounds are glycosides of aquayamycin, and among aquayamycin-group Antibiotics they are most closely related to P-1894B (vineomycin A1). All saquayamycins act on Gram-positive bacteria and inhibit the growth of adriamycin-sensitive and adriamycin-resistant P388 leukemia cells.

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