SARS-CoV-2-IN-106
SARS-CoV-2-IN-106 (compound 19) is a SARS-CoV-2 papain-like protease inhibitor with the IC50 values of 0.44 μM and 0.18 μM for PLpro enzymatic and viral replication ,respectively.
For research use only. We do not sell to patients.
- CAS No.: 2863607-73-0
- Formula: C31H38FN5O2
- Molecular Weight:531.66
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | CC50 |
>10 μM
Compound: 8
|
Cytotoxicity against human HeLa cells expressing hACE2 assessed as cell viability treated for 72 hrs by Cell Titer Glo assay
Cytotoxicity against human HeLa cells expressing hACE2 assessed as cell viability treated for 72 hrs by Cell Titer Glo assay
|
[PMID: 35620927] |
Chemical Information
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CAS No. 2863607-73-0
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Molecular Weight 531.66
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Formula C31H38FN5O2
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SMILES
C[C@@H](N1CCC(CC1)C(NCC2=CC(NC(N3CCN(CC3)C)=O)=CC(F)=C2)=O)C4=CC=CC5=C4C=CC=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)