SB 247083
SB 247083 is a selective, competitive and orally active endothelin-A receptor antagonist with a Ki of 0.41 nM. SB 247083 shows a Ki of 467 nM to endothelin-B receptor. SB 247083 shows a Kb of 3.5 nM for ET-1-induced contraction of rat aorta. SB 247083 can be used for the research of cardiovascular disease.
For research use only. We do not sell to patients.
- CAS No.: 188186-61-0
- Formula: C34H33ClN2O7
- Molecular Weight:617.09
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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ETA 0.41 nM (Ki) |
ETB 467 nM (Ki) |
Chemical Information
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CAS No. 188186-61-0
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Molecular Weight 617.09
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Formula C34H33ClN2O7
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SMILES
COC(C=C1C(OCC1)=C2)=C2C/C(C(O)=O)=C\C3=C(C4=C(C=C(C=C4)Cl)OCC5=C(C=CC=C5)C(O)=O)N(N=C3)CCCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SB 247083 Related Classifications
HY-106337 Related Classifications
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