1. Antibody-drug Conjugate/ADC Related
  2. Drug-Linker Conjugates for ADC
  3. SC-VC-PAB-MMAE

SC-VC-PAB-MMAE 

Cat. No.: HY-126681
Handling Instructions

SC-VC-PAB-MMAE is a drug-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the cleavable linker SC-VC-PAB.

For research use only. We do not sell to patients.

SC-VC-PAB-MMAE Chemical Structure

SC-VC-PAB-MMAE Chemical Structure

CAS No. : 2259318-46-0

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Description

SC-VC-PAB-MMAE is a drug-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the cleavable linker SC-VC-PAB[1].

IC50 & Target[1]

Auristatin

 

Molecular Weight

1348.62

Formula

C₆₈H₁₀₅N₁₁O₁₇

CAS No.

2259318-46-0

SMILES

O=C([[email protected]](CCCNC(N)=O)NC([[email protected]](C(C)C)NC(CCCCC(ON1C(CCC1=O)=O)=O)=O)=O)NC(C=C2)=CC=C2COC(N(C)[[email protected]@H](C(C)C)C(N[[email protected]@H](C(C)C)C(N(C)[[email protected]@H]([[email protected]@H](C)CC)[[email protected]](OC)CC(N3[[email protected]]([[email protected]](OC)[[email protected]@H](C)C(N[[email protected]@H]([[email protected]@H](O)C4=CC=CC=C4)C)=O)CCC3)=O)=O)=O)=O

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

SC-VC-PAB-MMAEDrug-Linker Conjugates for ADCInhibitorinhibitorinhibit

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SC-VC-PAB-MMAE
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