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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
308 Results for "
APC/CCDC20
" in MedChemExpress (MCE) Product Catalog:
Products (308)
308 Results for "APC/CCDC20" in MCE Product Catalog:
Cat. No.: HY-P87420A
Synonyms: HSPC214, ANAPC11, Anaphase-promoting complex subunit 11, APC11, Cyclosome subunit 11, Hepatocellular carcinoma-associated RING finger protein
Cat. No.: HY-P8F053J
Synonyms: Mouse IgG1, κ Isotype Ctrl Antibody,IgG1, κ-APC-Cy7,MOPC-21
Cat. No.: HY-P8F048J
Synonyms: CD274 (PD-L1),CD274-APC-Cy7,29E.2A3
Cat. No.: HY-P8F051J
Synonyms: Mouse IgG2a, κ Isotype Ctrl Antibody,IgG2a, κ -APC-Cy7,MOPC-173
Cat. No.: HY-P8F052J
Synonyms: Mouse IgG2b, κ Isotype Ctrl Antibody,IgG2b, κ -APC-Cy7,MPC-11
Cat. No.: HY-P8F062J
Synonyms: CD45R(B220),CD45R-APC-Cy7,RA3-6B2
Cat. No.: HY-P8F069I
Synonyms: Ly-6G/Ly-6C (Gr-1),GR-1-APC,RB6-8C5
Cat. No.: HY-145414
CAS No.: 2559734-98-2
Target:
Research Areas:
DYSP-C34 is a potent, biocompatible, and ultrasound (US)-triggered multifunctional molecular machine. DYSP-C34 has multiple favorable properties, such as improved lipophilic/hydrophilic balance, intensified US-induced ROS production capacity, and better cellular permeability, resulting in the excellent tumor target efficiency and notable sonodynamic therapy (SDT)-mediated tumor regression. DYSP-C34 exhibits mild immunogenicity by stimulating APCs directly .
Cat. No.: HY-P8F069J
Synonyms: Ly-6G/Ly-6C (Gr-1),GR-1-APC-Cy7,RB6-8C5
Cat. No.: HY-137849
CAS No.: 2171388-28-4
RK-582 is a tankyrase inhibitor, antitumor agent, and orally bioavailable growth inhibitor, with an IC50 of 36.1 nM against human tankyrase-1 and an IC50 of 39.2 nM against human tankyrase-2. In APC-mutated colorectal cancer cells, the sensitivity to RK-582 correlates with the level of active β-catenin, while drug resistance associates with PIK3CA mutation. RK-582 can be used for the research of colorectal cancer .
Cat. No.: HY-P10925
CAS No.: 3044032-95-0
Synonyms: FOG-001; I-66
Cat. No.: HY-108442R
CAS No.: 442644-28-2
Target:
Research Areas:
JW67 (Standard) is the analytical standard of JW67 (HY-108442). This product is intended for research and analytical applications. JW67 inhibits the canonical Wnt signaling with an IC50 of 1.17μM . JW67 affects the multiprotein complex consisting of β-catenin/GSK-3β/AXIN/APC/CK1 that rapidly reduces active β-catenin with a subsequent downregulation of Wnt target genes. JW67 also inhibits colorectal cancer cell growth .
Cat. No.: HY-179228
CAS No.: 1246964-08-8
Target:
Research Areas:
AN02 is a derivative of Curcumin (HY-N0005). AN02 inhibits the proliferation and clonogenicity, migration and invasion of ovarian cancer cells. AN02 dose-dependently upregulates the expression of APC and mediates the degradation of CTLA-4 through SMAD4. In the small xenograft model, AN02 significantly inhibits tumor growth and reverses the tumor immune-suppressive microenvironment. AN02, when combined with Ipilimumab (HY-P9901), can enhance efficacy and inhibit epithelial-mesenchymal transition. AN02 can be used for the study of ovarian cancer .
Cat. No.: HY-P83713M
Synonyms: Integrinalpha-X; Itgax; CD11antigen-likefamilymemberC; Leukocyteadhesionreceptorp150+95; CD11c
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
