59 Results for "

B-form dsDNA

" in MedChemExpress (MCE) Product Catalog:
Products (59)

59 Results for "B-form dsDNA" in MCE Product Catalog:

Cat. No.: HY-P2754
CAS No.: 9013-53-0
Target:  

Endonuclease Bacterial

Research Areas:  

Infection

Micrococcal nuclease is a secreted nuclease from Staphylococcus aureus. It digests single-stranded and double-stranded DNA (ssDNA and dsDNA) as well as RNA, cleaves oligonucleotide linkers with T-T sites, and cuts neutrophil extracellular traps and biofilm extracellular DNA into mononucleotides and dinucleotides. Micrococcal nuclease stimulates the formation of Staphylococcus aureus biofilms and mediates immune evasion. It triggers on-demand release of antibiotics from hydrogel coatings, prolongs the formation of neutrophil extracellular traps, and promotes the dissemination and survival of MRSA during infection. Micrococcal nuclease is applicable to research and characterization related to Staphylococcus aureus infection .
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Cat. No.: HY-E70579
CAS No.: 9037-44-9
Target:  

DNA/RNA Synthesis

Research Areas:  

Others

Exonuclease III is a nuclease for specifically targeting double-stranded DNA (dsDNA). Exonuclease III is a DNA repair-associated nuclease with apurinic/apyrimidinic (AP)-endonuclease and 3'→5' exonuclease activities. Exonuclease III cleaves the ssDNA at 5'-bond of phosphodiester from 3' to 5' end by both exonuclease and endonuclease activities .
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Cat. No.: HY-W013049S1
CAS No.: 29823-26-5
Synonyms: Behenic acid-d43
Docosanoic acid-d43 (Behenic acid-d43) is the deuterium labeled Docosanoic acid (HY-W013049). Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a Kd of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in humans .
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Cat. No.: HY-W013049S4
CAS No.: 1219804-98-4
Synonyms: Behenic acid-d4-1
Docosanoic acid-d4-1 (Behenic acid-d4-1) is the deuterium labeled Docosanoic acid (HY-W013049). Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a Kd of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in humans .
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Cat. No.: HY-148411
CAS No.: 167362-48-3
Synonyms: LJP 394 free base
Target:  

DNA/RNA Synthesis

Research Areas:  

Inflammation/Immunology

Abetimus (LJP 394 free base) is an immunosuppressant consisting of four double-stranded DNA (dsDNA) oligonucleotides. Abetimus is capable of crosslinking anti-dsDNA antibodies on the surface of B cells, and decreases anti-dsDNA antibodies levels. Abetimus has the potential for research of systemic lupus erythematosus .
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Cat. No.: HY-E70381
Target:  

Endonuclease

Research Areas:  

Cancer

dsDNase is a highly specific double-strand DNA (dsDNA) endonuclease that quickly and efficiently removes contaminating DNA from PCR master mixes .
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Cat. No.: HY-W013049S6
CAS No.: 2785462-39-5
Synonyms: Behenic acid-13C4
Docosanoic acid- 13C4 (Behenic acid- 13C4) is the 13C-labeled Docosanoic acid (HY-W013049). Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a Kd of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in vivo .
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Cat. No.: HY-118138
CAS No.: 106224-67-3
Research Areas:  

Cancer

NC-182 is an anti-tumor agent and DNA intercalator with a preference for B-form DNA. NC-182 can also promote the unwinding of Z-form DNA to B-form. NC-182 has a potent inhibitory effect on multidrug-resistant and sensitive tumors.
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Cat. No.: HY-E70604
Target:  

DNA/RNA Synthesis

Research Areas:  

Others

E. coli DNA ligase is a NAD +-dependent DNA ligase that catalyzes the formation of a phosphodiester bond between the complementary 3′-OH and 5′-P ends of dsDNA .
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Cat. No.: HY-P11351
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

Precursor-HhH is a nucleic acid-binding peptide capable of non-specific interactions with RNA and double-stranded DNA (dsDNA). Precursor-HhH is promising for research of nucleic acid-targeted therapeutics .
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Cat. No.: HY-162852
Target:  

G-quadruplex

Research Areas:  

Cancer

OAF89 is a small molecule that interacts with G-Quadruplexes (G4s) and dsDNA with an IC50 of 1.07 μM in normal lung epithelial cells BEAS-2B .
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Cat. No.: HY-W013049R
CAS No.: 112-85-6
Synonyms: Behenic acid (Standard)
Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a Kd of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in humans .
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Cat. No.: HY-149900
CAS No.: 2982270-24-4
Research Areas:  

Infection

Antiviral agent 33 (compound 1c) is a double-stranded DNA (dsDNA) virus inhibitor with IC50 values of 0.0790 and 0.1572 µM for VACV and AdV5, respectively. Antiviral agent 33 also has potential for oral administration .
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Cat. No.: HY-W190974
CAS No.: 132196-66-8
Synonyms: Perylene, 3-ethynyl-
Research Areas:  

Others

3-Ethynylperylene (Perylene, 3-ethynyl-) is a polyaromatic hydrocarbon with five fused rings and has a terminal propargyl group. 3-Ethynyl perylene possesses intrinsic fluorescence and pyrene derivatives are known for their ability to intercalate dsDNA. The propargyl group can react with azide-bearing compounds to form stable triazole rings.
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Cat. No.: HY-P5768
CAS No.: 2771233-98-6
Research Areas:  

Others

2× ST-tag II is an oligopeptide that can link proteins and dsDNA molecules in an efficient, rapid and specific manner. 2× ST-tag II is a peptide ligand of ST Tactin (STN). 2× ST-tag II specifically binds to ST Tactin. 2× ST-tag II can be used to construct DNA-protein hybrids .
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Cat. No.: HY-P5768A
Research Areas:  

Cancer

2× ST-tag II TFA is an oligopeptide that can link proteins and dsDNA molecules in an efficient, rapid and specific manner. 2× ST-tag II is a peptide ligand of ST Tactin (STN). 2× ST-tag II TFA specifically binds to ST Tactin. 2× ST-tag II TFA can be used to construct DNA-protein hybrids .
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Cat. No.: HY-W013049S
CAS No.: 1208430-53-8
Synonyms: Behenic acid-d4
Docosanoic acid-d4 (Behenic acid-4) is deuterium labeled Docosanoic acid (HY-W013049). Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a Kd of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in humans .
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Cat. No.: HY-W013049S2
CAS No.: 71607-34-6
Synonyms: Behenic acid-d2
Docosanoic acid-d2 (Behenic acid-d2) is deuterium labeled Docosanoic acid (HY-W013049). Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a Kd of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in humans .
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Cat. No.: HY-W013049S5
CAS No.: 1193721-65-1
Synonyms: Behenic acid-d4-2
Docosanoic acid-d4-2 (Behenic acid-d4-2) is the deuterium labeled Docosanoic acid (HY-W013049). Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a Kd of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in humans .
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Cat. No.: HY-D0150A
CAS No.: 2394903-71-8
(Z)-Thiazole Orange iodide is an asymmetric cyanine dye whose fluorescence highly depends on the local environment.(Z)-Thiazole Orange iodide is essentially dark in solution; however, its fluorescence increases a thousandfold when (Z)-Thiazole Orange iodide is introduced into double-stranded DNA and RNA (dsDNA or dsRNA). The maximum absorption of Thiazole Orange in complex with DNA is 509 nm, and the maximum emission is 532 nm. Thiazole Orange solution is widely used for determining the percentage of reticulocytes in human peripheral blood with microscopy and flow cytometry.
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