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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
43 Results for "
CPD self-cleavage
" in MedChemExpress (MCE) Product Catalog:
Products (43)
43 Results for "CPD self-cleavage" in MCE Product Catalog:
Cat. No.: HY-RS03089
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CPD Human Pre-designed siRNA Set A contains three designed siRNAs for CPD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-168662
CAS No.: 2139329-57-8
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Palbociclib-CH2COOH is a Ligands for Target Protein for PROTACs. Palbociclib-CH2COOH can serve as an active control for the target protein ligand of CPD-39 (HY-168664) and CPD-10 (HY-168660) .
Cat. No.: HY-144028
CAS No.: 2583778-77-0
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Compound cpd-1 is a small molecule Trks inhibitor with good antitumor activity .
Cat. No.: HY-158340
CAS No.: 2770471-05-9
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TYK2 ligand 1 is a TYK2 ligand in the synthesis of PROTAC-based TYK2 degrader (CPD-155, HY-158142) .
Cat. No.: HY-168663
CAS No.: 3055814-59-7
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E3 Ligase Ligand-linker Conjugate 131 is a conjugate of E3 ligase ligand and linker that serve as a key intermediate for the synthesis of complete PROTAC molecule CPD-10 HY-168660 .
Cat. No.: HY-168668
CAS No.: 3055816-67-3
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E3 Ligase Ligand-linker Conjugate 132 is a conjugate of E3 ligase ligand and linker that serve as a key intermediate for the synthesis of complete PROTAC molecule CPD-39 (HY-168664) .
Cat. No.: HY-20240
CAS No.: 1239589-52-6
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tert-Butyl (6-aminospiro[3.3]heptan-2-yl)carbamate is a linker that can be used for synthesis of PROTAC degrader CPD-39 (HY-168664) .
Cat. No.: HY-134621
CAS No.: 2488868-36-4
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P300-IN-1 (cpd205) is a Histone acetylase p300 inhibitor .
Cat. No.: HY-153441
CAS No.: 1954722-22-5
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AXL-IN-15 (cpd391) is a potent Axl inhibitor with both Ki and IC50 <1 nM. AXL-IN-15 can be used for research in cancer .
Cat. No.: HY-P4914
CAS No.: 120116-56-5
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Cat. No.: HY-P4523
CAS No.: 76079-06-6
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Cat. No.: HY-W585819R
CAS No.: 51930-97-3
Synonyms: 3-MPCD dipalmitate (Standard); 3-CPD dipalmitate (Standard)
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3-Chloropropane-1,2-diol dipalmitate (3-MPCD dipalmitate) Standard is the analytical standard of 3-Chloropropane-1,2-diol dipalmitate (HY-W585819). This product is intended for research and analytical applications. 3-Chloropropane-1,2-diol dipalmitate (3-MPCD dipalmitate) is a fatty acid ester of 3-monochloropropane-1,2-diol (3-MCPD) and a foodborne contaminant .
Cat. No.: HY-W471937
CAS No.: 874129-03-0
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α1b-AR antagonist 1 (Compound Cpd1) is a selective α1B-AR antagonist. Alpha1b-ar antagonist 1 can be used in the study of cardiovascular and central nervous system diseases .
Cat. No.: HY-179364
CAS No.: 1224565-08-5
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PLTP-IN-1 (cpd B) is a selective phospholipid transfer protein (PLTP) inhibitor with an IC50 of 1.6 μM. PLTP-IN-1 can block the phospholipid transfer mediated by PLTP and reduce the secretion of apolipoprotein B. PLTP-IN-1 has no effect on the level of triglycerides. PLTP-IN-1 can be used for the research of metabolic disease, such as hyperlipidemia .
Cat. No.: HY-W585819S
CAS No.: 3044743-84-9
Synonyms: 3-MPCD dipalmitate-13C3; 3-CPD dipalmitate-13C3
Cat. No.: HY-178488
CAS No.: 2468048-19-1
Target:
BRM/BRG1 ATP-IN-7 (Compound Cpd69) is a selective dual BRM (SMARCA2) and BRG1 (SMARCA4) inhibitor with IC50 values of 12 nM and 8 nM, respectively. BRM/BRG1 ATP-IN-7 is promising for research of BRM/BRG1-dependent cancers (e.g., non-small cell lung cancer, Ewing sarcoma) and virus-associated diseases (e.g., HPV infection) .
Cat. No.: HY-172455
CAS No.: 3023854-95-4
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TREK inhibitor-3 (Cpd8l) is a selective and BBB-permeable TREK-1 inhibitor with an IC50 of 0.81 μM. TREK inhibitor-3 has neuroprotective effects, which can significantly reduce the death of cortical neurons induced by oxygen-glucose deprivation/reoxygenation (OGD/R) and improve brain injury in mice models of middle cerebral artery occlusion/reperfusion (MCAO/R). TREK inhibitor-3 can be used in the research of ischemic stroke .
Cat. No.: HY-178490
CAS No.: 2468046-72-0
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BRM/BRG1 ATP-IN-8 (Compound Cpd14) is an orally active BRG1/BRM ATPase domain inhibitor. BRM/BRG1 ATP-IN-8 exerts antitumor effects by disrupting aberrant chromatin remodeling in cancer cells, inducing apoptosis and growth arrest. BRM/BRG1 ATP-IN-8 is promising for research of BRG1/BRM-dependent malignancies, including hematological cancers, prostate cancer, breast cancer, and Ewing's sarcoma .
Cat. No.: HY-169059
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Ferroptosis-IN-12 (Cpd-A1) is a ferroptosis inhibitor. Ferroptosis-IN-12 exhibits effective ferroptosis inhibition in Erastin (HY-15763)-treated mouse tubular epithelial cells (mTECs) and improves kidney function, alleviates renal tubular damage, and reduces inflammation in a dose-dependent manner in acute kidney injury (AKI) mouse models induced by ischemia/reperfusion (I/R) or cecal ligation and puncture (CLP). Ferroptosis-IN-12 demonstrates good plasma stability and high distribution in kidney tissues in pharmacokinetic studies in mice. Ferroptosis-IN-12 holds promise for research in the field of acute kidney injury (AKI) .
Cat. No.: HY-RS18891
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Cpd Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cpd gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
