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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
38 Results for "
Glycemic control
" in MedChemExpress (MCE) Product Catalog:
Products (38)
38 Results for "Glycemic control" in MCE Product Catalog:
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GPR120 Agonist 2 (example 206) is a GPR120 agonist that can be uesd for the study of type II diabetes and diseases associated with poor glycemic control .
Target:
Cat. No.: HY-W768181
CAS No.: 2751790-80-2
Synonyms: 1,5-Anhydro-D-glucitol-13C6
Cat. No.: HY-P11044
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Cat. No.: HY-112668B
CAS No.: 1174038-86-8
Synonyms: SP2086 hydrochloride
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Retagliptin (SP2086) hydrochloride is a potent inhibitor of beta-amino acids and dipeptidyl peptidase-4 (DPP-4). Retagliptin (SP2086) hydrochloride inhibits type 2 diabetes and improves glycemic control by prolonging the action of intestinal hormones such as glucagon-like peptide-1 (GLP-1) .
Cat. No.: HY-162513
CAS No.: 1123219-12-4
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DPP-4-IN-10 (compound 1) is a DPP-4 inhibitor. DPP-4-IN-10 is orally active. DPP-4-IN-10 blocks the degradation of GLP-1 and GIP, which may improve glycemic control in type 2 diabetes (T2MD) .
Cat. No.: HY-15408R
CAS No.: 865759-25-7
Synonyms: SYR-472 (Standard)
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Trelagliptin (Standard) is the analytical standard of Trelagliptin. This product is intended for research and analytical applications. Trelagliptin (SYR-472) is a potent, orally active and highly selective DPP-4 inhibitor with an IC50 of 4 nM. Trelagliptin succinate improves glycemic control in vivo and can be used for the study of type 2 diabetes mellitus (T2DM) .
Synonyms: BMS-801576
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Dapagliflozin-3-O-β-D-glucuronide (BMS-801576) is the metabolite of Dapagliflozin (HY-10450), and is formed in the liver and kidney by uridine diphosphate glucuronosyltransferase-1A9 (UGT1A9). Dapagliflozin is a selective inhibitor for SGLT2, that can be used to improve glycemic control and attenuate type 2 diabetes .
Cat. No.: HY-15408AR
CAS No.: 1029877-94-8
Synonyms: SYR-472 succinate (Standard)
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Trelagliptin (succinate) (Standard) is the analytical standard of Trelagliptin (succinate). This product is intended for research and analytical applications. Trelagliptin (SYR-472) succinate is a potent, orally active and highly selective DPP-4 inhibitor with an IC50 of 4 nM. Trelagliptin succinate improves glycemic control in vivo and can be used for the study of type 2 diabetes mellitus (T2DM) .
Cat. No.: HY-13967A
CAS No.: 865231-45-4
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AMG 837 sodium salt is an orally active, selective GPR40/FFA1 agonist with an EC50 of 1.5 nM against human GPR40. AMG 837 sodium salt stimulates insulin secretion in a glucose-dependent manner, and effectively improves glycemic control in both normal and diabetic rodent models . AMG 837 sodium salt binds to the BacA protein and impairs the survival and replication of Brucella. AMG 837 sodium salt can be used in research related to type 2 diabetes and brucellosis .
Cat. No.: HY-111294
CAS No.: 851389-35-0
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ASP4000 hydrochloride is an orally effective dipeptidyl peptidase 4 (DPP4) inhibitor, with an IC50 value of 2.25 nM against human recombinant DPP4, and exhibits hypoglycemic activity. By inhibiting DPP4 activity, ASP4000 hydrochloride reduces the degradation of active glucagon-like peptide-1 (GLP-1), thereby persistently increasing postprandial active GLP-1 levels and improving glycemic control. ASP4000 hydrochloride can be used in studies related to type 2 diabetes .
Cat. No.: HY-113075R
CAS No.: 154-58-5
Synonyms: 1,5-Anhydro-D-glucitol (Standard)
Cat. No.: HY-105074R
CAS No.: 196808-45-4
Synonyms: GI262570 (Standard); GI262570X (Standard)
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Farglitazar (Standard) is the analytical standard of Farglitazar (HY-105074). This product is intended for research and analytical applications. Farglitazar is a PPARγ agonist that has significant therapeutic benefits such as glycemic control in type 2 diabetic patients.
Cat. No.: HY-111353R
CAS No.: 1234844-11-1
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GPR120 Agonist 2 (Standard) is the analytical standard of GPR120 Agonist 2 (HY-111353). This product is intended for research and analytical applications. GPR120 Agonist 2 (example 206) is a GPR120 agonist that can be uesd for the study of type II diabetes and diseases associated with poor glycemic control .
Cat. No.: HY-189613
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EOS34295 is a dipeptidyl peptidase-IV (DPP-IV) inhibitor predicted to have oral activity. EOS34295 competitively binds to key residues in the active site of DPP-IV, inhibiting its enzymatic activity and blocking the degradation of incretins such as GLP-1/GIP, ultimately promoting insulin release to improve glycemic control. EOS34295 can be used in the study of type 2 diabetes .
Cat. No.: HY-14341
CAS No.: 528859-61-2
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E-6837 is a selective and orally active 5-HT6 receptor ligand. E-6837 demonstrates partial agonism at a presumably silent rat 5-HT6 receptor and full agonism at a constitutively active human 5-HT6 receptor by monitoring the cAMP signaling pathway. E-6837 induces hypophagia, reduces fat mass and body weight, and improves glycemic control. E-6837 can be used for the research of obesity .
Cat. No.: HY-167075
CAS No.: 851510-67-3
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ASP4000 free base is an orally effective dipeptidyl peptidase 4 (DPP4) inhibitor, with an IC50 value of 2.25 nM against human recombinant DPP4, and exhibits hypoglycemic activity. By inhibiting DPP4 activity, ASP4000 free base reduces the degradation of active glucagon-like peptide-1 (GLP-1), thereby persistently increasing postprandial active GLP-1 levels and improving glycemic control. ASP4000 free base can be used in studies related to type 2 diabetes .
Cat. No.: HY-P11604
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
