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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
92 Results for "
Intestinal bacteria
" in MedChemExpress (MCE) Product Catalog:
Products (92)
92 Results for "Intestinal bacteria" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-W013766
CAS No.: 72571-82-5
Target:
Research Areas:
Pipemidic acid trihydrate, a derivative of Piromidic acid, is an antibacterial agent. Pipemidic acid trihydrate inhibits DNA gyrase. Pipemidic acid trihydrate is active against gram-negative bacteria including Pseudomonas aeruginosa as well as some gram-positive bacteria. Pipemidic acid trihydrate can be used for the research of intestinal, urinary, and biliary tract infections .
Cat. No.: HY-B0396
CAS No.: 161715-24-8
Synonyms: L084
Target:
Research Areas:
Tebipenem pivoxil (L084 hydrobromide) is an orally active carbapenem Antibiotic. Tebipenem pivoxil acts as a substrate of OATP1A2 with high affinity for this transporter (Km = 41.1 μM) . Tebipenem pivoxil achieves intestinal absorption via carrier-mediated uptake and simple diffusion. Tebipenem pivoxil inhibits the growth of Gram-positive bacteria, Gram-negative bacteria, multidrug-resistant bacteria, and pathogens producing extended-spectrum β-lactamases. Tebipenem pivoxil eliminates intestinal infection pathogens and reduces mortality in septic mice. Tebipenem pivoxil can be used in research related to bacterial pneumonia, severe gastrointestinal infections, bacterial sepsis, complicated urinary tract infections, and acute pyelonephritis .
Cat. No.: HY-W145518
CAS No.: 9000-69-5
Synonyms: (R)-2-Hydroxypropionic acid sodium
Target:
Cat. No.: HY-W015954
CAS No.: 24347-58-8
Cat. No.: HY-B1773AS3
CAS No.: 152571-51-2
Synonyms: Oligolevulose
Cat. No.: HY-B0159
CAS No.: 127294-70-6
Synonyms: Q-35
Target:
Research Areas:
Balofloxacin (Q-35) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin can be used for the research of respiratory, intestinal, and urinary tract infections .
Cat. No.: HY-B1043
CAS No.: 19562-30-2
Category:
Infection Antibiotics Disease Research Antibacterial Endogenous metabolite Disease Research Fields Other Antibiotics
Target:
Synonyms: Isorhamnetin-3,7-diglucoside; Isorhamnetin diglucoside
Category:
Flavonols Flavonoids Brassica oleracea L. Metabolic Disease Phenols Polyphenols Plants Brassicaceae Disease Research Fields
Target:
Cat. No.: HY-17580S
CAS No.: 2143934-06-7
Cat. No.: HY-W250120
CAS No.: 37220-17-0
Cat. No.: HY-W007355S
CAS No.: 111399-60-1
Synonyms: 3-Methylindole-d3; 3-Methyl-1H-indole-d3
Cat. No.: HY-108695
CAS No.: 80226-00-2
Category:
Human Gut Microbiota Metabolites Phenols Polyphenols Endogenous metabolite Disease Research Fields Cancer
Target:
Synonyms: Ursodeoxycholate (Standard); Ursodiol (Standard); UDCA (Standard)
Cat. No.: HY-W007355R
CAS No.: 83-34-1
Synonyms: 3-Methylindole (Standard); 3-Methyl-1H-indole (Standard)
Cat. No.: HY-W007355S1
CAS No.: 697807-03-7
Synonyms: 3-Methylindole-d8; 3-Methyl-1H-indole-d8
Cat. No.: HY-W008030
CAS No.: 2243-47-2
3-Aminobiphenyl is a chemical isomer of 4-ABP. 3-Aminobiphenyl can inhibit the growth of human intestinal bacteria Bifidobacterium infantis ATCC 15697, B. bifidium ATCC 11863, Clostridium perfringens ATCC 13124, Escherichia coli ATCC 25922, E. coli ATCC 35218, Enterobacter cloacae ATCC 13047 and Salmonella typhimurium TA98, TA100, YG1041. 3-Aminobiphenyl can be used as a biomarker of exposure to aromatic amines from cigarette smoke .
Cat. No.: HY-B0819
CAS No.: 14816-18-3
Target:
Insecticide Cholinesterase (ChE) Cytochrome P450 Autophagy Reactive Oxygen Species (ROS) Apoptosis Bcl-2 Family Caspase COX Keap1-Nrf2 TNF Receptor Interleukin Related Bacterial
Research Areas:
Phoxim is an organophosphorus pesticide and an orally active inhibitor of cholinesterase and CYP3A, which induces neurotoxicity in Caenorhabditis elegans and causes nephrotoxicity characterized by glomerular atrophy and interstitial fibrosis. Phoxim induces inhibition of the autophagy pathway. Phoxim induces dopaminergic neuron degeneration and exacerbates Aβ-induced paralysis. Phoxim damages enterocytes and disrupts intestinal barrier integrity. Phoxim induces ROS accumulation. Phoxim induces mitochondrial apoptosis, involving upregulation of Bad, Bax, caspase-3, and caspase-9 and downregulation of Bcl-2. Phoxim inhibits mitochondrial functional enzymes (COX, Ca 2+-Mg 2+-ATPase, SDH). Phoxim upregulates Nrf2 mRNA expression in the jejunal mucosa. Phoxim increases TNF-α and decreases IL-6 and IL-8 in the intestinal mucosa. Phoxim alters gut microbial composition by increasing total bacteria and Escherichia coli and reducing Lactobacillus. Phoxim enhances energy metabolism in silver carp by upregulating key glycolytic and gluconeogenic enzymes. Phoxim is used in research on neurodegenerative diseases, nephrotoxicity, intestinal oxidative stress and barrier dysfunction, and bacterial sepsis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
