Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
43 Results for "
MCI
" in MedChemExpress (MCE) Product Catalog:
Products (43)
43 Results for "MCI" in MCE Product Catalog:
Cat. No.: HY-120810
CAS No.: 476148-82-0
Synonyms: DDP-225 hydrate hydrochloride
Target:
Research Areas:
MCI-225 (DDP-225) hydrate hydrochloride is a selective and orally active noradrenaline (NA) reuptake inhibitor with 5-HT3 receptor antagonism. MCI-225 hydrate hydrochloride has antidepressant-like and anxiolytic-like properties. MCI-225 hydrate hydrochloride can be used for the study of anxiety disorder .
Synonyms: MCI 154 hydrochloride
Target:
Research Areas:
Senazodan (MCI 154) (hydrochloride), as a Ca 2+ sensitiser, shows inhibition effect on PDE III .
Cat. No.: HY-123498
CAS No.: 99487-26-0
Synonyms: DDP 225 (dehydratase)
Target:
Research Areas:
MCI-225 dehydratase is an orally active and selective noradrenaline reuptake inhibitor. MCI-225 dehydratase also is a 5-HT3 antagonist and shows antidepressant effects in vivo .
Cat. No.: HY-101693
CAS No.: 98326-32-0
Synonyms: MCI 154
Target:
Research Areas:
Senazodan (MCI 154) is a Ca 2+ sensitiser, and also shows inhibition effect on PDE III .
Cat. No.: HY-10564S1
Synonyms: MCI-9042-d4
Cat. No.: HY-10564S
CAS No.: 2934185-00-7
Synonyms: MCI-9042-d3
Cat. No.: HY-RS08229
Target:
Research Areas:
MCIDAS Human Pre-designed siRNA Set A contains three designed siRNAs for MCIDAS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-B1558
CAS No.: 90293-01-9
Synonyms: MCI-2016 free base
Target:
Research Areas:
Bifemelane is a nootropic compound. Bifemelan causes the first peak by stimulating release from intracellular Ca 2+ stores and the second by capacitive entry through store–operated Ca 2+ channels. Bifemelane will be provided as a pharmacological tool for basic studies on astrocytes .
Cat. No.: HY-B0375AR
CAS No.: 141396-28-3
Synonyms: MD-805 monohydrate (Standard); MCI-9038 monohydrate (Standard)
Target:
Research Areas:
Argatroban (monohydrate) (Standard) is the analytical standard of Argatroban (monohydrate). This product is intended for research and analytical applications. Argatroban (monohydrate) (MD-805 (monohydrate)) is a direct, selective thrombin inhibitor.
Cat. No.: HY-10933S
CAS No.: 1286653-21-1
Synonyms: BDP 12-d10
Cat. No.: HY-B0375S1
Synonyms: MD-805-13C6 hydrochloride; MCI-9038-13C6 hydrochloride
Cat. No.: HY-B0375S
CAS No.: 1356847-56-7
Synonyms: MD-805-d3; MCI-9038-d3
Cat. No.: HY-173481
CDK9-IN-37 (Compound 24) is a CDK9 inhibitor (EC50: 5.5 nM) with weak inhibition on other CDK isoforms, showing high selectivity. CDK9-IN-37 has significant antiproliferative activity against acute myeloid leukemia MOLM-13 cells (IC50: 0.034 μM). CDK9-IN-37 inhibits the CDK9 signaling pathway, reduces the phosphorylation level of RNAP II CTD (Ser2), downregulates the anti-apoptotic protein McI-1, induces cell apoptosis, and arrests the cell cycle at the G2/M phase. CDK9-IN-37 can be used in the study of acute myeloid leukemia (AML) .
Cat. No.: HY-17550R
CAS No.: 314728-85-3
Synonyms: DM-235 (Standard)
Target:
Research Areas:
Sunifiram (Standard) is the analytical standard of Sunifiram. This product is intended for research and analytical applications. Sunifiram (DM-235) is an ampakine-like compound and an agonist of AMPA receptor with oral activity. Sunifiram can increase the release of acetylcholine in the rat cerebral cortex and exhibits potent cognitive enhancement effects with better nootropic activity compared to piracetam (HY-B0585). Sunifiram is promising for research in neurodegenerative diseases such as mild cognitive impairment (MCI) and Alzheimer's disease (AD) .
Cat. No.: HY-101481R
CAS No.: 91503-79-6
Target:
Reference Standards COX Apoptosis MEK ERK PPAR AMPK NF-κB Interleukin Related TNF Receptor STAT Wnt
Research Areas:
Flurbiprofen axetil (Standard) is the analytical standard of Flurbiprofen axetil. This product is intended for research and analytical applications. Flurbiprofen axetil is a non-selective COX inhibitor and a nonsteroidal anti-inflammatory agent with anti-inflammatory and analgesic effects. Flurbiprofen axetil inhibits basal-like breast cancer metastasis by inhibiting the MEK/ERK signaling pathway. Flurbiprofen axetil can promote neuroprotection after focal cerebral ischemia in rats by partially activating PPAR-γ. Flurbiprofen axetil alleviates cerebral ischemia/reperfusion injury by reducing inflammation in a transient global cerebral ischemia/reperfusion rat model. Flurbiprofen axetil can alleviate inflammatory responses and cognitive function in a mild cognitive impairment (MCI) SD rat model through the AMPKα/NF-κB signaling pathway .
Cat. No.: HY-101693AR
CAS No.: 98326-33-1
Synonyms: MCI 154 hydrochloride (Standard)
Research Areas:
Senazodan (hydrochloride) (Standard) is the analytical standard of Senazodan (hydrochloride) (HY-101693A). This product is intended for research and analytical applications. Senazodan (MCI 154) (hydrochloride), as a Ca2+ sensitiser, shows inhibition effect on PDE III .
Cat. No.: HY-FLB0099
CAS No.: 89-25-8
Synonyms: MCI-186 solution
Target:
Research Areas:
Cardiovascular Disease Infection Neurological Disease Inflammation/Immunology Cancer
Edaravone solution is mainly composed of Edaravone (HY-B0099). Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator. Edaravone can improve the neurological symptoms, daily living activities and functional impairments caused by acute cerebral infarction.
Cat. No.: HY-FLB0375A
CAS No.: 141396-28-3
Synonyms: MD-805 monohydrate solution; MCI-9038 monohydrate solution
Target:
Research Areas:
Argatroban solution is mainly composed of Argatroban monohydrate (HY-B0375A). Argatroban monohydrate is a direct, selective thrombin inhibitor with anticoagulant properties, and can be used to alleviate motor paralysis caused by ischemic cerebral infarction.
Cat. No.: HY-P84562A
Synonyms: MCI1; LRP-8; APOER2; HSZ75190
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
