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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
116 Results for "
SN-2
" in MedChemExpress (MCE) Product Catalog:
Products (116)
116 Results for "SN-2" in MCE Product Catalog:
Cat. No.: HY-W127380
CAS No.: 146797-82-2
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ROC-0929 (compound 13a) is a potent and selective inhibitor of secreted phospholipases A2 (sPLA2s) with an IC50 of 80 nM, specially targeting hGX. ROC-0929 inhibits the phosphorylation of ERK1/2 and p-38. Secreted phospholipases A2 (sPLA2s) are a family of disulfide-rich, Ca 2+-dependent enzymes that hydrolyze the sn-2 position of glycero-phospholipids to release a fatty acid and a lysophospholipid. ROC-0929 has the potential for researching inflammation related diseases .
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1,2-Dioleoyl-3-linoleoyl-rac-glycerol (OOL) is a triacylglycerol containing oleic acid at the sn-1 and sn-2 positions and linoleic acid at the sn-3 position. It is found in a variety of seed and vegetable oils, including pumpkin seed, olive, and sesame oils.
Cat. No.: HY-W343736
CAS No.: 67303-93-9
Synonyms: 1,3-DPPE; 1,3-Dipalmitoyl-SN-glycero-2-PE
1,3-Dipalmitoyl-glycero-2-phosphoethanolamine is a phospholipid containing the saturated long-chain (16:0) stearic acid inserted at the sn-1 and sn-3 positions and PE at the sn-2 site. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
Cat. No.: HY-141614
CAS No.: 61596-53-0
Synonyms: Phosphatidylcholine Diarachidoyl; 1,2-DAPC; L-α-Diarachidonoyl lecithin
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1,2-Diarachidoyl-sn-glycero-3-phosphocholine (1,2-DAPC) is a phospholipid containing the saturated long-chain (20:0) arachidic acid inserted at the sn-1 and sn-2 positions. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
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1,2-Dilinoleoyl-sn-glycerol is a diacylglycerol (DAG) with linoleic acid (HY-N0729) (18:2) side chains attached at both the sn-1 and sn-2 positions . 1,2-Dilinoleoyl-sn-glycerol can be prepared from L-dilinoleoylphosphatidylcholine via hydrolysis with phospholipase C [2] .
Cat. No.: HY-W440982A
CAS No.: 6753-56-6
Synonyms: (Rac)-PC(18:0/18:1); (Rac)-2-Oleoyl-1-stearoyl-SN-glycero-3-phosphocholine
Cat. No.: HY-W923483
CAS No.: 95403-34-2
Synonyms: 1-O-Hexadecyl-2-oleoyl-SN-glycero-3-phosphocholine
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C16-18:1 PC (1-O-Hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine), also known as 1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine (HOPC), is a member of the platelet-activating factor (PAF) family of glycerophospholipids and serves as a pro-inflammatory lipid mediator with diverse biological and pharmacological effects; it features a mono-ether structure with an oleoyl chain (18:1) ester-linked at the sn-2 position and a hexadecyl chain (16:0) ether-linked at the sn-1 position.
Cat. No.: HY-W440957
CAS No.: 69441-09-4
Synonyms: PC(16:0/14:0); 1-palmitoyl-2-myristoyl-SN-glycero-3-phosphocholine
PMPC is a phosphatidylcholine with asymmetrical fatty acid. Palmitic acid occupies sn-1 position while myristic acid is placed at the sn-2 position.
Cat. No.: HY-W800733
CAS No.: 73548-69-3
Synonyms: 1,2-Dilauroyl-SN-glycero-3-phosphorylglycerol; PG(12:0/12:0)
DLPG is a phospholipid containing lauric acid (12 chain fatty acid) inserted at the sn-1 and sn-2 positions. Its phosphate group is attached to glycerol. It is used in the generation of micelles, liposomes, and other artificial membranes.
Cat. No.: HY-W590536
CAS No.: 82765-47-7
Synonyms: 1-Palmitoyl-2-Lauroyl-SN-glycero-3-Phosphatidylcholine; 1-Palmitoyl-2-Lauroyl-SN-glycero-3-Phosphocholine
1,2-PLPC is a phospholipid containing palmitoyl (16:0) and lauryl (12:0) acyl substituents at the sn-1 and sn-2 positions, respectively. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
Cat. No.: HY-175120
CAS No.: 129581-47-1
Synonyms: 1,2,3-Tri-10(Z)-pentadecenoyl glycerol
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Tri-10(Z)-pentadecenoin (1,2,3-Tri-10(Z)-pentadecenoyl glycerol) is a triacylglycerol that contains 10(Z)-pentadecenoic acid at the sn-1, sn-2, and sn-3 positions.
Cat. No.: HY-113925
CAS No.: 108321-06-8
Synonyms: 1,2-DLPA Sodium; (2R)-2,3-bis(dodecanoyloxy)propyl hydrogen phosphate sodium
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1,2-Dilauroyl-sn-glycero-3-phosphate (1,2-DLPA) sodium is a phospholipid containing the medium-chain (12:0) lauric acid inserted at the sn-1 and sn-2 positions. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
Cat. No.: HY-W713925
CAS No.: 89019-63-6
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Diheptanoyl Thio-PC is a substrate for all phospholipase A2s (PLA2s) with the exception of cPLA2 and PAF-acetyl hydrolase (PAF-AH).1 Interaction of this compound with a PLA2 results in cleavage of the sn-2 fatty acid generating a free thiol on the lysophospholipid. This free thiol can be detected using chromogenic substrates such as DTNB (Ellman’s reagent) and DTP.
Cat. No.: HY-W127408
CAS No.: 20246-55-3
Cat. No.: HY-176085
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Heptanoyl thio-PC is a sn-2 thiol-labeled Phospholipase A2 (HY-P3029) (PLA2) substrate that can be used to detect the activity of Phospholipase A2 .
Cat. No.: HY-125744
CAS No.: 113881-60-0
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Palmitoyl thio-PC is a chromogenic substrate specific for PLA2 with a palmitoyl thioester at the sn-2 position. Palmitoyl thio-PC could be used to measure bee-venom sPLA2 activity in a phospholipid system .
Cat. No.: HY-W725327
CAS No.: 66414-33-3
Synonyms: 1,2-Dipropionyl-SN-glycero-3-Phosphatidylcholine; 1,2-Dipropionyl-SN-glycero-3-Phosphocholine; PC(3:0/3:0)
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1,2-Dipropionyl-sn-glycero-3-PC is a phospholipid containing propionic acid at the sn-1 and sn-2 positions. It has been used to study the interaction between water and the phosphocholine headgroup in aqueous solutions.
Cat. No.: HY-170631
CAS No.: 68069-77-2
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1,2-Dielaidoyl-3-palmitoyl-rac-glycerol is a triacylglycerol that contains Elaidic acid (HY-113016) in the sn-1 and sn-2 positions and Palmitic acid (HY-N0830) in the sn-3 position.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
