109 Results for "

attack

" in MedChemExpress (MCE) Product Catalog:
Products (109)

109 Results for "attack" in MCE Product Catalog:

Cat. No.: HY-113338
CAS No.: 5614-64-2
Purity:  98.37%
Synonyms: 8-Oxoguanine; 8-oxo-Gua
8-Hydroxyguanine is a DNA damage product under oxidative stress, which is formed when hydroxyl radicals attack guanine in DNA. 8-Hydroxyguanine induces mutagenesis and leads to a transversion from G to T. 8-Hydroxyguanine is a marker of DNA oxidative damage .
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Cat. No.: HY-P99517
CAS No.: 2411871-58-2
Synonyms: JNJ-63898081; JNJ-081

Target:  

CD3 PSMA

Research Areas:  

Cancer

Voxalatamab (JNJ-63898081) is a bispecific IgG4 antibody targeting PSMA and CD3. Voxalatamab attacks PSMA-expressing tumor cells by activating T cells. Voxalatamab has anticancer activity and is being studied for the treatment of solid tumors such as prostate cancer .
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Cat. No.: HY-B1738A
CAS No.: 94-63-3
Target:  

Cholinesterase (ChE)

Research Areas:  

Neurological Disease

Pralidoxime iodide is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime iodide reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime iodide is an antidote for organophosphate poisoning .
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Cat. No.: HY-P99322
CAS No.: 1531594-08-7
Synonyms: LFG316; Anti-Human C5 Recombinant Antibody

Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Tesidolumab (LFG316) is a fully-human IgG1/λ anti-C5 monoclonal antibody of 143 kDa (without glycosylation). Tesidolumab (LFG316) blocks cleavage of C5 and prevents subsequent formation of the membrane attack complex .
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Cat. No.: HY-N0300R
CAS No.: 2934-97-6
Synonyms: DL-Tetrahydropalmatine (Standard)
Tetrahydropalmatine (Standard) is the analytical standard of Tetrahydropalmatine. This product is intended for research and analytical applications. Tetrahydropalmatine possesses analgesic effects. Tetrahydropalmatine acts through inhibition of amygdaloid release of dopamine to inhibit an epileptic attack in rats .
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Cat. No.: HY-P99638
CAS No.: 2456407-94-4
Synonyms: ALXN-1720

Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Gefurulimab (ALXN-1720) is a high-affinity antibody inhibitor targeting complement protein C5, which can specifically bind to C5 and inhibit its cleavage into C5a and C5b. Gefurulimab can block the activation of the terminal complement pathway and reduce inflammatory damage. Gefurulimab can effectively reduce the formation of membrane attack complex (MAC) and has good pharmacokinetic properties. Gefurulimab can be used to study kidney and autoimmune diseases related to abnormal activation of the complement system, such as IgA nephropathy, lupus nephritis, and myasthenia gravis .
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Cat. No.: HY-B1777R
CAS No.: 71-44-3
Synonyms: NSC 268508 (Standard); Neuridine (Standard)
Spermine (Standard) is the analytical standard of Spermine. This product is intended for research and analytical applications. Spermine (NSC 268508) functions directly as a free radical scabenger to protect DNA from free radical attack. Spermine has antiviral effects.
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Cat. No.: HY-P990302

Target:  

nAChR

Research Areas:  

Inflammation/Immunology

Anti-Human/Rat/Fish AChR Antibody (Mab35) is an anti-human/rat/fish AChR IgG1 monoclonal antibody. Anti-Human/Rat/Fish AChR Antibody (Mab35) can attack the AChR of neuromuscular junctions. Anti-Human/Rat/Fish AChR Antibody (Mab35) can be used for the construction of myasthenia gravis models .
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Cat. No.: HY-W196368
CAS No.: 2217-60-9
Thymohydroquinone is a COX-2 inhibitor and anti-SARS-CoV-2 agent that induces cytotoxicity, antiproliferative effects and inhibits tumor growth. Thymohydroquinone cannot scavenge superoxide radicals via σ (hydrogen atom transfer) and π-π attacks with superoxide anions. Thymohydroquinone can be used in research related to squamous cell carcinoma, fibrosarcoma and coronavirus disease 2019 (SARS-CoV-2 infection) .
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Cat. No.: HY-111603R
CAS No.: 20123-80-2
Research Areas:  

Others

Calcium dobesilate (Standard) is the analytical standard of Calcium dobesilate. This product is intended for research and analytical applications. Calcium dobesilate, a vasoprotective, is widely used in chronic venous disease, diabetic retinopathy and the symptoms of haemorrhoidal attack in many countries.
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Cat. No.: HY-P10532
CAS No.: 121196-80-3
Target:  

PKC

Research Areas:  

Others Inflammation/Immunology

Myelin basic protein, MBP (68-86) is the portion of the 68th to 86th amino acid residues in the MBP protein sequence. Myelin basic protein, MBP (68-86) can act as an autoantigen, triggering the immune system to attack its own myelin. Myelin basic protein, MBP (68-86) is used as one of the immunogens in the experimental autoimmune encephalomyelitis (EAE) animal model to study immune responses associated with multiple sclerosis (MS) .
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Cat. No.: HY-P991629

Target:  

Ser/Thr Protease

Research Areas:  

Inflammation/Immunology

C1 Esterase Inhibitor (Human) is a C1 Esterase inhibitor derived from human plasma. C1 Esterase Inhibitor (Human), a glycoprotein, is a serum protease inhibitor (serpin) that binds covalently and inactivates C1r, C1s, and mannan-binding protein-associated proteases (MASPs). C1 Esterase Inhibitor (Human) has anti-inflammatory effects. C1 Esterase Inhibitor (Human) can be used to prevent angioedema attacks associated with hereditary angioedema .
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Cat. No.: HY-108814
CAS No.: 460738-38-9
Synonyms: DX-88
Target:  

Kallikrein

Research Areas:  

Cardiovascular Disease

Ecallantide (DX-88) is a specific plasma kallikrein inhibitor. Ecallantide inhibits the production of bradykinin. Ecallantide can be used to prevent acute attacks of angioedema .
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Cat. No.: HY-18206S
CAS No.: 1356905-39-9
Synonyms: MK-521-d5
Lisinopril-d5 is the deuterium labeled Lisinopril. Lisinopril (MK-521) is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks.
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Cat. No.: HY-B0562
CAS No.: 135-07-9
Methyclothiazide is an orally active antihypertensive agent and a diuretic agent. Methyclothiazide leads to a reduction of the vascular response to the action of endogenous vasoconstricting stimuli, such as Norepinephrine (HY-13715). Methyclothiazide is against voltage-dependent Ca-channel (VDCC) activity in vitro .
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Cat. No.: HY-B1658
CAS No.: 158747-02-5
Synonyms: (R)-Frovatriptan; SB 209509; VML 251
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

Frovatriptan is a potent 5-HT1B//D receptor agonist and has the highest 5-HT1B potency in the triptan class. Frovatriptan is apparently cerebroselective. Frovatriptan is efficacious and even superior in some endpoints also when taken during the headache phase in migraine attacks with aura .
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Cat. No.: HY-112575
CAS No.: 64679-65-8
Tiazotic acid is a metabolic agent that has immunomodulatory, anti-inflammatory, antioxidant, anti-ischemic, cardio- and endothelioprotective, antiplatelet, hepatoprotective activities. Tiazotic acid increases the levels of eNOS. Tiazotic acid also reduces the level of D-dimer in the blood, which reduces the risks of heart attacks and strokes in post-COVID syndrome .
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Cat. No.: HY-B0157AS
CAS No.: 1795138-23-6
Synonyms: HC 20-511-d3 fumarate
Ketotifen-d3 (fumarate) is the deuterium labeled Ketotifen fumarate. Ketotifen (HC 20511) fumarate is a second-generation noncompetitive H1-antihistamine and mast cell stabilizer, which is used to prevent asthma attacks .
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Cat. No.: HY-B1738
CAS No.: 6735-59-7
Target:  

Cholinesterase (ChE)

Research Areas:  

Neurological Disease

Pralidoxime is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime is an antidote for organophosphate poisoning .
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Cat. No.: HY-177801
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

XQ-P3 sodium is an aptamer that binds to PD-L1. XQ-P3 can inhibit the PD-1/PD-L1 interaction and restore the function of T cells to detect and attack tumor cells.
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