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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
35 Results for "
caspase-3 substrate
" in MedChemExpress (MCE) Product Catalog:
Products (35)
35 Results for "caspase-3 substrate" in MCE Product Catalog:
Cat. No.: HY-P2615
CAS No.: 210344-94-8
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Cat. No.: HY-P4403
CAS No.: 223538-61-2
Synonyms: (Z-Asp-Glu-Val-Asp)₂-Rhodamine 110
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Cat. No.: HY-P10452
CAS No.: 400727-81-3
Cat. No.: HY-P3475
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Cat. No.: HY-P2614
CAS No.: 189696-20-6
Cat. No.: HY-P10162A
Cat. No.: HY-P4400
CAS No.: 219138-08-6
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Cat. No.: HY-B1751S1
Cat. No.: HY-P10083
CAS No.: 189684-55-7
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Cat. No.: HY-W338079
CAS No.: 189684-50-2
Cat. No.: HY-W115674
CAS No.: 1668-99-1
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Quinidine hydrochloride is an orally active antiarrhythmic agent. Quinidine hydrochloride reduces the expression level of P-gp, inhibits P-gp-mediated efflux, increases the intracellular accumulation of P-gp substrates, induces PARP cleavage and Caspase-3 activation, and elevates the proportion of Apoptotic cells at the sub-G1 phase. Quinidine hydrochloride exerts sustained block and open-channel block effects on IK(f). Quinidine hydrochloride alters the urinary metabolic ratio of Amphetamine, modulates the Pentylenetetrazol-induced seizure threshold, and regulates the anticonvulsant effect of Dextromethorphan. Quinidine hydrochloride can be used in studies related to uterine sarcoma and seizures .
Cat. No.: HY-101310R
CAS No.: 31137-74-3
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Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
SYM 2081 (Standard) is the analytical standard of SYM 2081 (HY-101310). This product is intended for research and analytical applications. SYM 2081 is a kainate receptor agonist. SYM 2081 is a substrate of EAAT1 (Km of 54 μM). SYM 2081 inhibits EAAT2-mediated glutamate transport (Kb is 3.4 μM in Xenopus oocytes), modulates Apoptotic signaling pathways (increases Bcl-2 and decreases Bax/caspase-3 expression). SYM 2081 exhibits neuroprotective activity. SYM 2081 can be used in the study of hypoxic-ischemic brain damage and inflammatory or neuropathic pain .
Cat. No.: HY-106419A
CAS No.: 80427-58-3
Synonyms: Benflurone hydrochloride
Benfluron hydrochloride is an Apoptosis inducer and inhibitor of the HIV-1 Rev-RRE complex, with an IC50 of 5.0 μM against the HIV-1 Rev-RRE complex. Benfluron hydrochloride induces p53 activation, and triggers phosphorylation of Chk1 at serine 345, Chk2 at threonine 68, as well as ERK1/2 at threonine 202 and tyrosine 204. Benfluron hydrochloride activates Caspase 8, Caspase 9 and Caspase 3/7, inhibits HIV-1 viral transcription, and acts as a substrate for 11β-HSD 1 and cytosolic carbonyl reductase. Benfluron hydrochloride can be used in research related to leukemia and HIV-1 infection .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
