![3-[2-(3-Hydroxypropoxy)ethoxy]propan-1-ol](https://file.medchemexpress.com/product_pic/hy-w591308.gif "Click to View 3-[2-(3-Hydroxypropoxy)ethoxy]propan-1-ol Product Detail")
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
70 Results for "
Bioisosteric replacement
" in MedChemExpress (MCE) Product Catalog:
Products (70)
70 Results for "Bioisosteric replacement" in MCE Product Catalog:
Cat. No.: HY-118409
CAS No.: 110763-24-1
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VPC-3033 is an androgen receptor antagonist. VPC-3033 has a strong androgen DHT replacement potency (IC50: 0.625-2.5 μM), can effectively inhibit androgen receptor transcriptional activity (IC50=0.3 μM), and has a strong androgen receptor degradation ability. In addition, VPC-3033 exhibits significant anti-androgen receptor activity against prostate cancer cells resistant to Enzalutamide (HY-70002) .
Cat. No.: HY-P2446
CAS No.: 83539-08-6
Synonyms: APTAA-LHRH
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Cat. No.: HY-121465
CAS No.: 67964-87-8
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Stearoyl serotonin is a hybrid molecule patterned after arachidonoyl serotonin. Arachidonoyl serotonin is a dual antagonist of fatty acid amide hydrolase (FAAH) and the transient receptor potential vanilloid-type 1 (TRPV1) channel, reducing both acute and chronic peripheral pain. The effects of replacing the arachidonoyl portion with the saturated 18-carbon stearoyl moiety have not been studied. However, replacement of arachidonate with saturated 11- or 12-carbon fatty acids produces compounds that potently inhibit capsaicin-induced TRPV1 channel activation (IC50=0.76 μM) without blocking FAAH-mediated hydrolysis of arachidonoyl ethanolamine (IC50 > 50 μM).
Cat. No.: HY-129281
CAS No.: 1797979-43-1
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Benzedrone hydrochloride is an analog of Mephedrone characterized by the replacement of the amino methyl group with a benzyl moiety .
Cat. No.: HY-W742484
CAS No.: 67968-46-1
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1-Linoleoyl-(2S)-glycerol is a lipid with a structure similar to that of linoleic acid. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
Cat. No.: HY-W413662
CAS No.: 119649-45-5
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4-[(4-Methoxyphenyl)methoxy]butan-1-ol is a compound with a methyl phenol group and a butanol tail. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
Cat. No.: HY-W800816
CAS No.: 1561-55-3
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1,2-Di-O-tetradecyl-rac-glycerol is a hydrophobic compound that has been found to occure naturally in the body. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
Cat. No.: HY-168322
CAS No.: 888327-74-0
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2-Hydroxy nile red trifluoromethanesulfonate is a fluorescent probe, that enters into oligodeoxyribonucleic acid as a nucleotide replacement. 2-Hydroxy nile red trifluoromethanesulfonate can be used as a DNA probe for detecting the polar changes in tumor microenvironments .
Cat. No.: HY-134106
CAS No.: 116467-63-1
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N-Boc-erythro-sphingosine is composed of t-butyl ester protected N-acetylsphingosine with a fatty acid tail. The hydroxy group enables further derivatization or replacement with other reactive functional groups. The t-butyl group can be deprotected under mild acidic conditions.
Cat. No.: HY-W591972
CAS No.: 75351-33-6
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6-Hydroxyhexyl 4-methylbenzenesulfonate is a six carbon linker containing a hydroxyl group and a tosyl group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The tosyl group is a very good leaving group for nucleophilic substitution reactions.
Cat. No.: HY-W800616
CAS No.: 88299-47-2
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C11-PEG4-alcohol is a linker with an aliphatic carbon chain and a PEG chain. The hydrophilic PEG chain increases the water solubility of the compounds in the aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
Cat. No.: HY-W591308
CAS No.: 92144-80-4
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3-[2-(3-hydroxypropoxy)ethoxy]propan-1-ol is a linker consisting of two terminal hydroxyl groups. The partial PEG chain increases the water solubility of a compound in aqueous media. The hydroxyl groups enables further derivatization or replacement with other reactive functional groups.
Cat. No.: HY-W702728
CAS No.: 63326-63-6
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rac 1-Palmitoyl-2-chloropropanediol is a monoacylglycerol of palmitic acid at the sn-1 position and a chloride group at the sn-2 position. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The chlorine is a good leaving group and can undergo substitution reactions.
Cat. No.: HY-W598195
CAS No.: 122161-09-5
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11-Azido-1-undecanol is a compound with an azide head and a undecanol tail. The azide (N3) group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
Cat. No.: HY-W153502
CAS No.: 85475-01-0
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MeNH-PEG2-OH is a PEG linker containing a hydroxyl group with a methylamine group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The methylamine group is reactive with carboxylic acids, carbonyls (ketone, aldehyde) etc.
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Dienestrol diacetate is a synthetic nonsteroidal phenolic compound with estrogenic activity. Dienestrol diacetate can mimic the effects of estrogen in vivo, affecting the reproductive system and other related biological processes. Dienestrol diacetate is being studied for the inhibition of hormone-related diseases, such as estrogen deficiency. Dienestrol diacetate's potential applications also include possible use in hormone replacement therapy .
Cat. No.: HY-130159
CAS No.: 1186025-29-5
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Hydroxy-PEG12-t-butyl ester is a PEG linker containing a hydroxyl group with a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Cat. No.: HY-W403732
CAS No.: 333754-13-5
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8-Iodooct-7-yn-1-ol comprises an iodo-propargyl group attached to a 6-carbon tail with a terminal hydroxyl group. The iodine (I) acts as a good leaving group for nucleophilic substitution reactions. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
Cat. No.: HY-W710422
CAS No.: 86008-21-1
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1-O-Octadecyl-2-O-benzyl-rac-glycerol is a diacylglycerol that contains octadecyl alcohol at the sn-1 and benzyl alcohol at the sn-3 position. It is used in the synthesis of alkylphospholipids containing modifications of the phosphocholine moiety with antitumor activities. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
Cat. No.: HY-116655A
CAS No.: 2855229-28-4
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Hydroxy-PEG1-acid sodium is a PEG linker containing a hydroxyl group with a terminal carboxylic acid (as sodium salt form). The free acid form is not stable due to the reaction of OH with PEG-COOH group to form polymer. The sodium salt form is stable for storage and shipping. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
