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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
98 Results for "
CD47
" in MedChemExpress (MCE) Product Catalog:
Products (98)
98 Results for "CD47" in MCE Product Catalog:
Cat. No.: HY-P991755
Target:
Research Areas:
Cat. No.: HY-P990723
CAS No.: 2749520-17-8
Cat. No.: HY-P991560
CAS No.: 2987103-72-8
Cat. No.: HY-P991027
CAS No.: 2928515-36-8
Synonyms: PT-886
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Cat. No.: HY-P991561
CAS No.: 2691109-74-5
Cat. No.: HY-P991016
CAS No.: 2928515-21-1
Synonyms: PT-217
Target:
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Cat. No.: HY-P991004
CAS No.: 2923687-56-1
Synonyms: LB-101
Target:
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Itanistomig (LB-101) is a tetravalent bispecific antibody targeting PD-L1 and CD47. Itanistomig blocks PD-L1 and achieves tumor enrichment through binding to PD-L1, and also exerts conditional CD47 blocking activity via cleavage of the hinge linker in the PD-L1-positive tumor microenvironment. Itanistomig induces antibody-dependent cellular phagocytosis in human CD14 + cells and drives tumor regression. Itanistomig can be used in research related to solid tumors .
Cat. No.: HY-P10371
CAS No.: 1505523-99-8
Synonyms: txCD47
Research Areas:
Cat. No.: HY-143224A
CAS No.: 896700-07-5
NCGC00138783 free base is a selective inhibitor targeting CD47/SIRPα axis, with an IC50 of 50 µM. NCGC00138783 free base directly blocks the interaction between CD47 and SIRPα axis .
Cat. No.: HY-P990954
CAS No.: 2850355-94-9
Synonyms: IMM-0306
Amulirafusp alfa (IMM-0306) is a fusion protein of CD20 monoclonal antibody (mAb) with the CD47 binding domain of SIRPα, with human CD20 Kd 2.45 nM and human CD47 Kd 4.91 nM. Amulirafusp alfa binds to CD20 and CD47 on B cells, engages FcɣR, blocks CD47-SIRPα interaction, activates macrophages, NK cells, and complement cascade, mediates phagocytosis and cytotoxicity, inhibits apoptosis of Jurkat-CSR cells, reverses IL-16 tumor-promoting effects, and binds human/cynomolgus CD47 but not mouse/rat CD47. Amulirafusp alfa can be used for the research of hematological malignancies, relapsed or refractory CD20-positive B-cell non-Hodgkin’s lymphoma, relapsed or refractory B-cell non-Hodgkin lymphoma, and activated B-cell-like diffuse large B-cell lymphoma .
Cat. No.: HY-P10813
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Cat. No.: HY-P990899
CAS No.: 2889449-09-4
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Cat. No.: HY-P990962
CAS No.: 2850355-96-1
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Cat. No.: HY-P991923
Cat. No.: HY-P74289
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD47; Antigen Identified By Monoclonal Antibody 1D8; Prev. MER6; Integrin-Associated Protein; Leukocyte Surface Antigen CD47; Rh-Related Antigen; IAP; CD47 Glycoprotein; Antigenic Surface Determinant Protein OA3; Integrin-Associated Signal Transducer; OA3; CD47 Antigen; CD47 Antigen (Rh-Related Antigen, Integrin-Associated Signal Transducer); Protein MER6; CD47 Molecule; Integrin Associated Protein
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P11205
CAS No.: 2378833-51-1
Synonyms: Cys-txCD47
Research Areas:
Cat. No.: HY-P78611
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD47; Antigen Identified By Monoclonal Antibody 1D8; Prev. MER6; Integrin-Associated Protein; Leukocyte Surface Antigen CD47; Rh-Related Antigen; IAP; CD47 Glycoprotein; Antigenic Surface Determinant Protein OA3; Integrin-Associated Signal Transducer; OA3
Species:
Rabbit
Source:
HEK293
Cat. No.: HY-P78639
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD47; Antigen Identified By Monoclonal Antibody 1D8; Prev. MER6; Integrin-Associated Protein; Leukocyte Surface Antigen CD47; Rh-Related Antigen; IAP; CD47 Glycoprotein; Antigenic Surface Determinant Protein OA3; Integrin-Associated Signal Transducer; OA3
Species:
Canine
Source:
HEK293
Cat. No.: HY-P78710
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD47; Antigen Identified By Monoclonal Antibody 1D8; Prev. MER6; Integrin-Associated Protein; Leukocyte Surface Antigen CD47; Rh-Related Antigen; IAP; CD47 Glycoprotein; Antigenic Surface Determinant Protein OA3; Integrin-Associated Signal Transducer; OA3
Species:
Mouse
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
