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Spevatamig

(Synonyms: PT-886)
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Based on 1 Customer Validation

HY-P991027 is an CD47/CLDN18-targeting (H-γ1_L-κ)_(H-γ1_L-κ) type bispecific antibody.

For research use only. We do not sell to patients.

  • Purity: ≥99.0%
  • CAS No.: 2928515-36-8
  • Molecular Weight:145.181 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Spevatamig
  • Experimental Validation Results for Spevatamig
  • Experimental Validation Results for Spevatamig
  • Experimental Validation Results for Spevatamig
  • Spevatamig Chemical Structure
    Spevatamig Chemical Structure
CAS No.: 2928515-36-8
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Spevatamig Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    IgG1-kappa

  • 1/16

    Immobilized CD47 Protein, Human (HEK293, His, HY-P7336) can bind Spevatamig. The EC50 for this effect is 158 ng/mL.

  • 1/16

    Immobilized Claudin-18/CLDN18.2 Protein-VLP, Human (HEK293, HY-P78368) can bind Spevatamig. The EC50 for this effect is 15.05 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 Juakat cells with Spevatamig (HY-P991027, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Spevatamig Chemical Structure
    1/16
  • Spevatamig
  • Immobilized CD47 Protein, Human (HEK293, His, HY-P7336) can bind Spevatamig. The EC50 for this effect is 158 ng/mL.
  • Immobilized Claudin-18/CLDN18.2 Protein-VLP, Human (HEK293, HY-P78368) can bind Spevatamig. The EC50 for this effect is 15.05 ng/mL.
  • Flow cytometric analysis of 1X106 Juakat cells with Spevatamig (HY-P991027, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • IgG1-kappa