Timdarpacept
Based on 1 Customer Validation
Timdarpacept (DNL310) is a recombinant SIRPa-Fc fusion protein that can activate macrophages to enhance anti-tumor activity by blocking CD47-SIRPa.
For research use only. We do not sell to patients.
- Purity: 99.95%
- CAS No.: 2749520-17-8
- Molecular Weight:80.561 kDa
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Fusion-SIRPA-IGHG1 Fc
Human
CD47
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
-
FPIA_[PROTEIN]2-FC
-
Immobilized CD47 Protein, Human (HEK293, HY-P72917) can bind Timdarpacept. The EC50 for this effect is 730 ng/mL.
Chemical Information
-
CAS No. 2749520-17-8
-
Appearance Liquid
-
Molecular Weight 80.561 kDa
-
Color Colorless to light yellow
-
Shipping
Shipping with dry ice.
-
Formulation
Please refer to the lot-specific COA for specific buffer information.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
-
Data Sheet (253 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Inhibitory Antibodies User Guide (603 KB)
References
[1]. Timdarpacept
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)